{"id":42457,"date":"2009-10-01T00:00:00","date_gmt":"2018-12-04T01:49:51","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/associations-between-dietary-fiber-and-inflammation-hepatic\/"},"modified":"2018-12-04T02:49:51","modified_gmt":"2018-12-04T01:49:51","slug":"associations-between-dietary-fiber-and-inflammation-hepatic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/associations-between-dietary-fiber-and-inflammation-hepatic\/","title":{"rendered":"Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk."},"content":{"rendered":"<p>Abstract<br \/>\nOBJECTIVE: To examine the relationship between dietary fiber and the risk of type 2 diabetes in older men and the role of hepatic and inflammatory markers. RESEARCH DESIGN AND METHODS: The study was performed prospectively and included 3,428 nondiabetic men (age 60-79 years) followed up for 7 years, during which there were 162 incident cases of type 2 diabetes. RESULTS: Low total dietary fiber (lowest quartile &lt; or =20 g\/day) was associated with increased risk of diabetes after adjustment for total calorie intake and potential confounders (relative risk -1.47 [95% CI 1.03-2.11]). This increased risk was seen separately for both low cereal and low vegetable fiber intake. Dietary fiber was inversely associated with inflammatory markers (C-reactive protein, interleukin-6) and with tissue plasminogen activator and gamma-glutamyl transferase. Adjustment for these markers attenuated the increased risk (1.28 [0.88-1.86]). CONCLUSIONS: Dietary fiber is associated with reduced diabetes risk, which may be partly explained by inflammatory markers and hepatic fat deposition.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-42457","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Primary Care and Population Health, University College Medical School, Hampstead Campus, University College London, London, UK. goya@pcps.ucl.ac.uk","annee":"2009","mois":"10","numero":"32:10","page":"1823-5","auteurs":[{"ID":16891,"post_author":"0","post_date":"2018-12-03 19:44:33","post_date_gmt":"2018-12-03 18:44:33","post_content":"","post_title":"Peter H Whincup","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"peter-h-whincup","to_ping":"","pinged":"","post_modified":"2018-12-03 19:44:33","post_modified_gmt":"2018-12-03 18:44:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/peter-h-whincup\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":16895,"post_author":"0","post_date":"2018-12-03 19:44:35","post_date_gmt":"2018-12-03 18:44:35","post_content":"","post_title":"S Goya Wannamethee","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"s-goya-wannamethee","to_ping":"","pinged":"","post_modified":"2018-12-03 19:44:35","post_modified_gmt":"2018-12-03 18:44:35","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/s-goya-wannamethee\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":42456,"post_author":"0","post_date":"2018-12-04 02:49:50","post_date_gmt":"2018-12-04 01:49:50","post_content":"","post_title":"Thomas","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"thomas-5","to_ping":"","pinged":"","post_modified":"2018-12-04 02:49:50","post_modified_gmt":"2018-12-04 01:49:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/thomas-5\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":15924,"post_author":"0","post_date":"2018-12-03 19:32:35","post_date_gmt":"2018-12-03 18:32:35","post_content":"","post_title":"Naveed Sattar","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"naveed-sattar","to_ping":"","pinged":"","post_modified":"2018-12-03 19:32:35","post_modified_gmt":"2018-12-03 18:32:35","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/naveed-sattar\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":16521,"post_author":"0","post_date":"2018-12-03 19:40:05","post_date_gmt":"2018-12-03 18:40:05","post_content":"","post_title":"Diabetes care","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"diabetes-care","to_ping":"","pinged":"","post_modified":"2018-12-03 19:40:05","post_modified_gmt":"2018-12-03 18:40:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/diabetes-care\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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