{"id":42416,"date":"2001-11-01T00:00:00","date_gmt":"2018-12-04T01:49:03","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/site-specific-differences-in-the-fatty-acid-composition-of\/"},"modified":"2018-12-04T02:49:03","modified_gmt":"2018-12-04T01:49:03","slug":"site-specific-differences-in-the-fatty-acid-composition-of","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/site-specific-differences-in-the-fatty-acid-composition-of\/","title":{"rendered":"Site-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesity."},"content":{"rendered":"

BACKGROUND:<\/strong>
\nAbdominal obesity is associated with coronary risk, although causality is not well established.<\/p>\n

OBJECTIVE:<\/strong>
\nIn an obese Mediterranean population, we measured the fatty acid composition of adipose tissue, its relation with dietary fatty acids and central fat deposition, and its influence on plasma lipids and insulin.<\/p>\n

DESIGN:<\/strong>
\nAdipose tissue samples were obtained from 84 obese patients (29 men, 55 women) aged 30-70 y (body mass index, in kg\/m²: 27-35). We measured concentrations of insulin and lipids in plasma and fatty acids in subcutaneous, omental, and perivisceral fat. Dietary fatty acid intake was assessed with a 7-d diet record.<\/p>\n

RESULTS:<\/strong>
\nThe population studied was normolipidemic and normoinsulinemic. There were important differences in fatty acid composition between tissue sites: saturated fatty acids were higher and monounsaturated fatty acids were lower in perivisceral than in subcutaneous fat (P < 0.05). Significant correlations were found for oleic, linoleic, alpha-linolenic, and total n-6 polyunsaturated fatty acids between the subject's habitual diet and adipose tissue composition. Oleic and n-3 fatty acids from adipose regions were negatively correlated with apolipoprotein B and triacylglycerols; adipose tissue 22:1n-9, 20:2n-6, stearic acid, and eicosapentaenoic acid were positively correlated with HDL and apolipoprotein A; and adipose tissue myristic acid was negatively correlated with apolipoprotein A (P < 0.05). Central obesity was positively associated with n-6 polyunsaturated fatty acids and inversely associated with monounsaturated fatty acids and n-3 polyunsaturated fatty acids in adipose tissue (P < 0.05).<\/p>\n

CONCLUSION:<\/strong>
\nThe differences found in the composition and metabolism of perivisceral, omental, and subcutaneous fats may indicate that their atherogenic capacities also differ.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-42416","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Physiology and Pharmacology, University of Murcia, Murcia, Spain.","annee":"2001","mois":"11","numero":"74:5","page":"585-591","auteurs":[{"ID":9295,"post_author":"0","post_date":"2018-12-03 18:09:32","post_date_gmt":"2018-12-03 17:09:32","post_content":"","post_title":"Marta Garaulet","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"marta-garaulet","to_ping":"","pinged":"","post_modified":"2018-12-03 18:09:32","post_modified_gmt":"2018-12-03 17:09:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/marta-garaulet\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":36962,"post_author":"0","post_date":"2018-12-04 01:09:19","post_date_gmt":"2018-12-04 00:09:19","post_content":"","post_title":"Perez-llamas","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"perez-llamas","to_ping":"","pinged":"","post_modified":"2018-12-04 01:09:19","post_modified_gmt":"2018-12-04 00:09:19","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/perez-llamas\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1720,"post_author":"0","post_date":"2018-12-03 16:01:56","post_date_gmt":"2018-12-03 15:01:56","post_content":"","post_title":"Am J Clin Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-clin-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:56","post_modified_gmt":"2018-12-03 15:01:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-clin-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nSite-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesity. - 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