{"id":41763,"date":"2009-11-01T00:00:00","date_gmt":"2018-12-04T01:37:57","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/soft-drink-consumption-is-associated-with-fatty-liver-disease\/"},"modified":"2018-12-04T02:37:57","modified_gmt":"2018-12-04T01:37:57","slug":"soft-drink-consumption-is-associated-with-fatty-liver-disease","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/soft-drink-consumption-is-associated-with-fatty-liver-disease\/","title":{"rendered":"Soft drink consumption is associated with fatty liver disease independent of metabolic syndrome."},"content":{"rendered":"<p>BACKGROUND\/AIMS: The independent role of soft drink consumption in non-alcoholic fatty liver disease (NAFLD) patients remains unclear. We aimed to assess the association between consumption of soft drinks and fatty liver in patients with or without metabolic syndrome. METHODS: We recruited 31 patients (age: 43+\/-12 years) with NAFLD and risk factors for metabolic syndrome, 29 patients with NAFLD and without risk factors for metabolic syndrome, and 30 gender- and age-matched individuals without NAFLD. The degree of fatty infiltration was measured by ultrasound. Data on physical activity and intake of food and soft drinks were collected during two 7-day periods over 6 months using a food questionnaire. Insulin resistance, inflammation, and oxidant-antioxidant markers were measured. RESULTS: We found that 80% of patients with NAFLD had excessive intake of soft drink beverages (&gt;500 cm(3)\/day) compared to 17% of healthy controls (p&lt;0.001). The NAFLD group consumed five times more carbohydrates from soft drinks compared to healthy controls (40% vs. 8%, p&lt;0.001). Seven percent of patients consumed one soft drink per day, 55% consumed two or three soft drinks per day, and 38% consumed more than four soft drinks per day for most days and for the 6-month period. The most common soft drinks were Coca-Cola (regular: 32%; diet: 21%) followed by fruit juices (47%). Patients with NAFLD with metabolic syndrome had similar malonyldialdehyde, paraoxonase, and C-reactive protein (CRP) levels but higher homeostasis model assessment (HOMA) and higher ferritin than NAFLD patients without metabolic syndrome (HOMA: 8.3+\/-8 vs. 3.7+\/-3.7 mg\/dL, p&lt;0.001; ferritin: 186+\/-192 vs. 87+\/-84 mg\/dL, p&lt;0.01). Logistic regression analysis showed that soft drink consumption is a strong predictor of fatty liver (odds ratio: 2.0; p&lt;0.04) independent of metabolic syndrome and CRP level. CONCLUSIONS: NAFLD patients display higher soft drink consumption independent of metabolic syndrome diagnosis. These findings might optimize NAFLD risk stratification.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-41763","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Liver Unit, Ziv Medical Center, Safed, Israel.\r\n\r\nComment in:\r\n\r\nJ Hepatol. 2010 Jun;52(6):954; author reply 954. \r\n","annee":"2009","mois":"11","numero":"51(5):918-24","page":"","auteurs":[{"ID":41759,"post_author":"0","post_date":"2018-12-04 02:37:55","post_date_gmt":"2018-12-04 01:37:55","post_content":"","post_title":"Abid","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"abid","to_ping":"","pinged":"","post_modified":"2018-12-04 02:37:55","post_modified_gmt":"2018-12-04 01:37:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/abid\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":41760,"post_author":"0","post_date":"2018-12-04 02:37:56","post_date_gmt":"2018-12-04 01:37:56","post_content":"","post_title":"Taha","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"taha","to_ping":"","pinged":"","post_modified":"2018-12-04 02:37:56","post_modified_gmt":"2018-12-04 01:37:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/taha\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":41761,"post_author":"0","post_date":"2018-12-04 02:37:56","post_date_gmt":"2018-12-04 01:37:56","post_content":"","post_title":"Nseir","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nseir","to_ping":"","pinged":"","post_modified":"2018-12-04 02:37:56","post_modified_gmt":"2018-12-04 01:37:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/nseir\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":41762,"post_author":"0","post_date":"2018-12-04 02:37:57","post_date_gmt":"2018-12-04 01:37:57","post_content":"","post_title":"J HEPATOL","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-hepatol","to_ping":"","pinged":"","post_modified":"2018-12-04 02:37:57","post_modified_gmt":"2018-12-04 01:37:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/j-hepatol\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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