{"id":41402,"date":"2010-08-01T00:00:00","date_gmt":"2018-12-04T01:32:06","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/a-3-year-mediterranean-style-dietary-intervention-may-modulate\/"},"modified":"2018-12-04T02:32:06","modified_gmt":"2018-12-04T01:32:06","slug":"a-3-year-mediterranean-style-dietary-intervention-may-modulate","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/a-3-year-mediterranean-style-dietary-intervention-may-modulate\/","title":{"rendered":"A 3-year Mediterranean-style dietary intervention may modulate the association between adiponectin gene variants and body weight change."},"content":{"rendered":"<p><strong>PURPOSE<\/strong>:<br \/>\nAdiponectin gene variations have been associated with obesity. There are few interventional studies analyzing this association. The aim of this study was to analyze the effects of a nutritional intervention with Mediterranean-style diet and three (-4034A\/C, +45T\/G, and +276 G\/T) adiponectin gene variants on 3-year body weight changes in high cardiovascular risk patients.<\/p>\n<p><strong>SUBJECTS AND METHODS<\/strong>:<br \/>\nA total of 737 participants, aged 55-80 at high cardiovascular risk were assigned to a low-fat diet or to a Mediterranean-style diet (MD) groups, one with high intake of virgin olive oil (VOO) and the other with high intake of nuts. Anthropometric parameters were taken at baseline and after 3-year follow-up, and the genotyping of the -4034A\/C, +45T\/G, and +276 G\/T polymorphisms was done.<\/p>\n<p><strong>RESULTS<\/strong>:<br \/>\nGG genotype of the +45T\/G polymorphism was associated with 3-year higher body weight gain (B = 1.399; B = 0.043). TT genotype of the +276G\/T polymorphism was linked to the highest 3-year body weight gain in men. Both Mediterranean diets appeared to reverse this effect (p for interaction = 0.053).<\/p>\n<p><strong>CONCLUSION<\/strong>:<br \/>\nAdiponectin gene variation appeared to be associated with 3-year body weight changes in a high cardiovascular risk population. This association may be modulated by a nutritional intervention with a Mediterranean-style diet.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-41402","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Irunlarrea 1, 31080, Pamplona, Navarra, Spain.","annee":"2010","mois":"8","numero":"49:5","page":"311-9","auteurs":[{"ID":1549,"post_author":"0","post_date":"2018-12-03 16:00:25","post_date_gmt":"2018-12-03 15:00:25","post_content":"","post_title":"Miguel Angel Mart\u00ednez-Gonz\u00e1lez","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"miguel-angel-martinez-gonzalez","to_ping":"","pinged":"","post_modified":"2018-12-03 16:00:25","post_modified_gmt":"2018-12-03 15:00:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/miguel-angel-martinez-gonzalez\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7876,"post_author":"0","post_date":"2018-12-03 17:53:51","post_date_gmt":"2018-12-03 16:53:51","post_content":"","post_title":"J Alfredo Martinez","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-alfredo-martinez","to_ping":"","pinged":"","post_modified":"2018-12-03 17:53:51","post_modified_gmt":"2018-12-03 16:53:51","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/j-alfredo-martinez\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":5267,"post_author":"0","post_date":"2018-12-03 17:26:08","post_date_gmt":"2018-12-03 16:26:08","post_content":"","post_title":"Cristina Razquin","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"cristina-razquin","to_ping":"","pinged":"","post_modified":"2018-12-03 17:26:08","post_modified_gmt":"2018-12-03 16:26:08","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/cristina-razquin\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":30026,"post_author":"0","post_date":"2018-12-03 23:26:51","post_date_gmt":"2018-12-03 22:26:51","post_content":"","post_title":"Eur J Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"eur-j-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 23:26:51","post_modified_gmt":"2018-12-03 22:26:51","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/eur-j-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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