{"id":41375,"date":"2009-12-01T00:00:00","date_gmt":"2018-12-04T01:31:37","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-antioxidant-intake-allergic-sensitization-and-allergic\/"},"modified":"2018-12-04T02:31:37","modified_gmt":"2018-12-04T01:31:37","slug":"dietary-antioxidant-intake-allergic-sensitization-and-allergic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-antioxidant-intake-allergic-sensitization-and-allergic\/","title":{"rendered":"Dietary antioxidant intake, allergic sensitization and allergic diseases in young children."},"content":{"rendered":"

Abstract
\nBACKGROUND: Allergic diseases have risen in prevalence over recent decades. The aetiology remains unclear but is likely to be a result of changing lifestyle and\/or environment. A reduction in antioxidant intake, consequent to reduced intake of fresh fruits and vegetables, has been suggested as a possible cause. OBJECTIVE: To investigate whether dietary antioxidant intake at age 5 was related to atopy at 5 and 8 years of age amongst children in an unselected birth cohort. METHODS: Children were followed from birth. Parents completed a validated respiratory questionnaire and children were skin prick tested at 5 and 8 years of age. Serum IgE levels were measured at age 5. At age 5, antioxidant intake was assessed using a semi-quantitative food frequency questionnaire (FFQ). A nutrient analysis program computed nutrient intake, and frequency counts of foods high in the antioxidant vitamins A, C and E were assessed. RESULTS: Eight hundred and sixty-one children completed both the respiratory and FFQ. Beta-carotene intake was associated with reduced risk of allergic sensitization at age 5 [0.80 (0.68-0.93)] and 8 [0.81 (0.70-0.94)]. In addition, beta-carotene intake was negatively associated with total IgE levels (P = 0.002). Vitamin E intake was associated with an increased risk of allergic sensitization [1.19 (1.02-1.39)], only at age 5. There was no association between antioxidant intakes and wheeze or eczema. CONCLUSION: Increased beta-carotene intake was associated with a reduced risk of allergic sensitization and lower IgE levels, in 5- and 8-year-old children. Dietary antioxidants may play a role in the development of allergic sensitization.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-41375","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"School of Translational Medicine, University of Manchester and NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.","annee":"2009","mois":"12","numero":"64:12","page":"1766-72","auteurs":[{"ID":31380,"post_author":"0","post_date":"2018-12-03 23:44:22","post_date_gmt":"2018-12-03 22:44:22","post_content":"","post_title":"Sumaiya Patel","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sumaiya-patel","to_ping":"","pinged":"","post_modified":"2018-12-03 23:44:22","post_modified_gmt":"2018-12-03 22:44:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sumaiya-patel\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":41373,"post_author":"0","post_date":"2018-12-04 02:31:36","post_date_gmt":"2018-12-04 01:31:36","post_content":"","post_title":"Woodcock","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"woodcock","to_ping":"","pinged":"","post_modified":"2018-12-04 02:31:36","post_modified_gmt":"2018-12-04 01:31:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/woodcock\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":31385,"post_author":"0","post_date":"2018-12-03 23:44:25","post_date_gmt":"2018-12-03 22:44:25","post_content":"","post_title":"Clare S Murray","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"clare-s-murray","to_ping":"","pinged":"","post_modified":"2018-12-03 23:44:25","post_modified_gmt":"2018-12-03 22:44:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/clare-s-murray\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":41374,"post_author":"0","post_date":"2018-12-04 02:31:37","post_date_gmt":"2018-12-04 01:31:37","post_content":"","post_title":"ALLERGY","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"allergy","to_ping":"","pinged":"","post_modified":"2018-12-04 02:31:37","post_modified_gmt":"2018-12-04 01:31:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/allergy\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nDietary antioxidant intake, allergic sensitization and allergic diseases in young children. - 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