{"id":41307,"date":"2010-03-01T00:00:00","date_gmt":"2018-12-04T01:30:27","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-predictors-of-the-insulin-like-growth-factor-system\/"},"modified":"2018-12-04T02:30:27","modified_gmt":"2018-12-04T01:30:27","slug":"dietary-predictors-of-the-insulin-like-growth-factor-system","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-predictors-of-the-insulin-like-growth-factor-system\/","title":{"rendered":"Dietary predictors of the insulin-like growth factor system in adolescent females: results from the dietary intervention study in children (disc)."},"content":{"rendered":"<p>Abstract<br \/>\nBACKGROUND: The insulin-like growth factor (IGF) system is associated with the adult diet and chronic disease. Childhood diet may influence chronic disease through its effect on the IGF system; however, there is limited information describing the dietary predictors of the IGF system in adolescents. OBJECTIVE: We examined associations between dietary food intake [fat, protein (animal and vegetable), carbohydrate, lactose, dietary fiber, calcium, zinc, and sodium] and serum IGF-I, IGF binding protein 1 (IGFBP-1), IGF binding protein 3 (IGFBP-3), and the IGF-I:IGFBP-3 molar ratio in adolescent females. DESIGN: One hundred fifty-nine adolescent females in the Dietary Intervention Study in Children (age range: 14-18 y; 0.2-6.3 y postmenarche) were included. The dietary intake was assessed via three 24-h dietary recalls. IGF-related biomarkers were determined by using radioimmunoassays. Associations between dietary intakes and biomarkers were assessed with Pearson&rsquo;s correlations and multivariable linear regression. Dietary intakes and biomarkers were logarithmically transformed; thus, beta coefficients represented percentages. RESULTS: In analyses adjusted for energy, age, and time since menarche, significant correlations (P &lt; 0.05) were as follows: IGF-I with total protein, lactose, calcium, and sodium; IGFBP-3 with total fat (inverse), lactose, fiber, and calcium; IGF-I\/IGFBP-3 with lactose and calcium; and IGFBP-1 with vegetable protein. In multivariable analyses, significant predictors of IGF-I were energy (beta = 0.14, P &lt; 0.05) and calcium (beta = 0.14, P &lt; 0.01), the significant predictor of IGFBP-3 was calcium (beta = 0.07, P &lt; 0.05), and significant predictors of IGFBP-1 were vegetable protein (beta = 0.49, P &lt; 0.05) and body mass index-for-age percentile (beta = -0.01, P &lt; 0.001). CONCLUSION: This study provides evidence that dietary intake affects IGF-related biomarkers-particularly elevated calcium with IGF-I and IGFBP-3 and elevated vegetable protein with IGFBP-1-and, to our knowledge, is novel in reporting these associations in adolescent females. The Dietary Intervention Study in Children was registered at clinicaltrials.gov as NCT00000459.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-41307","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Epidemiology, Michigan State University, East Lansing, MI, USA. kerverje@msu.edu","annee":"2010","mois":"3","numero":"91:3","page":"643-50","auteurs":[{"ID":41304,"post_author":"0","post_date":"2018-12-04 02:30:25","post_date_gmt":"2018-12-04 01:30:25","post_content":"","post_title":"Kerver","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kerver","to_ping":"","pinged":"","post_modified":"2018-12-04 02:30:25","post_modified_gmt":"2018-12-04 01:30:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kerver\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":41305,"post_author":"0","post_date":"2018-12-04 02:30:26","post_date_gmt":"2018-12-04 01:30:26","post_content":"","post_title":"Gardiner","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"gardiner","to_ping":"","pinged":"","post_modified":"2018-12-04 02:30:26","post_modified_gmt":"2018-12-04 01:30:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/gardiner\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":41306,"post_author":"0","post_date":"2018-12-04 02:30:26","post_date_gmt":"2018-12-04 01:30:26","post_content":"","post_title":"Dorgan","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dorgan","to_ping":"","pinged":"","post_modified":"2018-12-04 02:30:26","post_modified_gmt":"2018-12-04 01:30:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dorgan\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1720,"post_author":"0","post_date":"2018-12-03 16:01:56","post_date_gmt":"2018-12-03 15:01:56","post_content":"","post_title":"Am J Clin Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-clin-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:56","post_modified_gmt":"2018-12-03 15:01:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-clin-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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