{"id":40888,"date":"2010-06-01T00:00:00","date_gmt":"2018-12-04T01:23:38","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/"},"modified":"2018-12-04T02:23:38","modified_gmt":"2018-12-04T01:23:38","slug":"anthocyanins-are-bioavailable-in-humans-following-an-acute","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/","title":{"rendered":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice."},"content":{"rendered":"

Research suggests that anthocyanins from berry fruit may affect a variety of physiological responses, including endothelial function, but little information is available regarding the pharmacokinetics of these flavonoids in humans. To determine the pharmacokinetics of cranberry anthocyanins, a study was undertaken in 15 participants (age: 62 +\/- 8 y) with coronary artery disease. Blood and urine samples were collected between baseline (0 h) and 4 h after consumption of 480 mL cranberry juice (54% juice; 835 mg total polyphenols; 94.47 mg anthocyanins). Marked inter-individual differences in plasma anthocyanin pharmacokinetics were observed with maximum anthocyanin concentrations detected between 1 and 3 h. Cranberry anthocyanins were bioavailable but with notable differences in the maximum concentration and area under the curve(0-4h) between individual participants. The pattern of anthocyanin glucosides observed in plasma and urine generally reflected the relative concentration determined in the juice. Plasma concentrations of the individual anthocyanins ranged between 0.56 and 4.64 nmol\/L. Total recovery of urinary anthocyanin was 0.79 +\/- 0.90% of the dose delivered. These data are in agreement with the pharmacokinetics of anthocyanins from other foods suggesting that cranberry anthocyanins are poorly absorbed and rapidly removed from plasma. Observed concentrations of plasma anthocyanins appear insufficient to alter radical load or redox potential but may be adequate to affect signal transduction and\/or gene expression.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-40888","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA. paul.milbury@tufts.edu","annee":"2010","mois":"6","numero":"140:6","page":"1099-104","auteurs":[{"ID":18676,"post_author":"0","post_date":"2018-12-03 20:11:16","post_date_gmt":"2018-12-03 19:11:16","post_content":"","post_title":"Jeffrey B Blumberg","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jeffrey-b-blumberg","to_ping":"","pinged":"","post_modified":"2018-12-03 20:11:16","post_modified_gmt":"2018-12-03 19:11:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jeffrey-b-blumberg\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40886,"post_author":"0","post_date":"2018-12-04 02:23:37","post_date_gmt":"2018-12-04 01:23:37","post_content":"","post_title":"Joseph A Vita","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"joseph-a-vita","to_ping":"","pinged":"","post_modified":"2018-12-04 02:23:37","post_modified_gmt":"2018-12-04 01:23:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/joseph-a-vita\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40887,"post_author":"0","post_date":"2018-12-04 02:23:37","post_date_gmt":"2018-12-04 01:23:37","post_content":"","post_title":"Milbury","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"milbury","to_ping":"","pinged":"","post_modified":"2018-12-04 02:23:37","post_modified_gmt":"2018-12-04 01:23:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/milbury\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":32402,"post_author":"0","post_date":"2018-12-03 23:58:36","post_date_gmt":"2018-12-03 22:58:36","post_content":"","post_title":"J NUTR","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-nutr-2","to_ping":"","pinged":"","post_modified":"2018-12-03 23:58:36","post_modified_gmt":"2018-12-03 22:58:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/j-nutr-2\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nAnthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel<\/title>\n<meta name=\"description\" content=\"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice.\" \/>\n<meta property=\"og:description\" content=\"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/\",\"name\":\"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T01:23:38+00:00\",\"dateModified\":\"2018-12-04T01:23:38+00:00\",\"description\":\"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel","description":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice.","og_description":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice.","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/","name":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T01:23:38+00:00","dateModified":"2018-12-04T01:23:38+00:00","description":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice. - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/anthocyanins-are-bioavailable-in-humans-following-an-acute\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"Anthocyanins are bioavailable in humans following an acute dose of cranberry juice."}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/40888"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=40888"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=40888"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}