{"id":40601,"date":"2009-01-01T00:00:00","date_gmt":"2018-12-04T01:17:01","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/beta-carotene-and-alpha-tocopherol-in-healthy-overweight\/"},"modified":"2018-12-04T02:17:01","modified_gmt":"2018-12-04T01:17:01","slug":"beta-carotene-and-alpha-tocopherol-in-healthy-overweight","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/beta-carotene-and-alpha-tocopherol-in-healthy-overweight\/","title":{"rendered":"Beta-carotene and alpha-tocopherol in healthy overweight adults; depletion kinetics are correlated with adiposity."},"content":{"rendered":"<p>Abstract<br \/>\nHealthy overweight subjects (24 males, 68 females; mean age=48.8 years; body mass index=27.1+\/-4.9) participated in a randomized, double-blind, placebo-controlled crossover study with two periods of 28-day supplementation using a nutritional product composed primarily of dehydrated juice concentrates from mixed fruits and vegetables (JuicePlus +). Compared with placebo, supplementation for 28 days increased concentrations of serum beta-carotene by 264% (P &lt;0.001) and alpha-tocopherol by 14% (P &lt; 0.01). After crossover of the active group to placebo, beta-carotene and alpha-tocopherol declined via first-order kinetics, with serum half-lives (t (1\/2)) for beta-carotene and alpha-tocopherol determined to be 22.8+\/-3.1 and 4.6+\/-2.3 days, respectively. Depletion rates for beta-carotene correlated with adiposity (quartile 1, body mass index=21.96, t (1\/2)=17.6 days vs. quartile 4, body mass index=37.87, t (1\/2)=26.3 days; P &lt; 0.05). In conclusion, the supplementation period resulted in significantly elevated levels of beta-carotene and alpha-tocopherol, indicating bioavailability. These increased levels persisted 2-4 weeks after supplementation was discontinued, and the rates of depletion were correlated with the levels of general adiposity.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-40601","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Science and Technology, Natural Alternatives International, Inc., San Marcos, CA 92078, USA. jwise@nai-online.com","annee":"2009","mois":"0","numero":"60:1","page":"65-75","auteurs":[{"ID":40597,"post_author":"0","post_date":"2018-12-04 02:16:59","post_date_gmt":"2018-12-04 01:16:59","post_content":"","post_title":"Wise","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"wise-2","to_ping":"","pinged":"","post_modified":"2018-12-04 02:16:59","post_modified_gmt":"2018-12-04 01:16:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/wise-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40598,"post_author":"0","post_date":"2018-12-04 02:16:59","post_date_gmt":"2018-12-04 01:16:59","post_content":"","post_title":"Kaats","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kaats","to_ping":"","pinged":"","post_modified":"2018-12-04 02:16:59","post_modified_gmt":"2018-12-04 01:16:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kaats\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40599,"post_author":"0","post_date":"2018-12-04 02:17:00","post_date_gmt":"2018-12-04 01:17:00","post_content":"","post_title":"Preuss","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"preuss","to_ping":"","pinged":"","post_modified":"2018-12-04 02:17:00","post_modified_gmt":"2018-12-04 01:17:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/preuss\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40600,"post_author":"0","post_date":"2018-12-04 02:17:00","post_date_gmt":"2018-12-04 01:17:00","post_content":"","post_title":"Morin","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"morin","to_ping":"","pinged":"","post_modified":"2018-12-04 02:17:00","post_modified_gmt":"2018-12-04 01:17:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/morin\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":34493,"post_author":"0","post_date":"2018-12-04 00:30:38","post_date_gmt":"2018-12-03 23:30:38","post_content":"","post_title":"INT J FOOD SCI NUTR","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"int-j-food-sci-nutr-2","to_ping":"","pinged":"","post_modified":"2018-12-04 00:30:38","post_modified_gmt":"2018-12-03 23:30:38","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/int-j-food-sci-nutr-2\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Beta-carotene and alpha-tocopherol in healthy overweight adults; 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