{"id":40059,"date":"2010-01-01T00:00:00","date_gmt":"2018-12-04T01:08:05","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/"},"modified":"2018-12-04T02:08:05","modified_gmt":"2018-12-04T01:08:05","slug":"ppari-activation-by-culinary-herbs-and-spices","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/","title":{"rendered":"Pparα activation by culinary herbs and spices."},"content":{"rendered":"

Hyper- and dyslipidemia are risk factors for cardiovascular disease, the primary cause of death in industrialized countries. Peroxisome proliferators-activated receptor (PPAR) α activation is involved in various mechanisms that improve the lipid profile. We tested various plant extracts and their compounds to determine whether they stimulated PPAR α activity IN VITRO. Out of 34 tested plant extracts, nine exhibited low to moderate PPAR α transactivation, including caraway, chili pepper, nutmeg, licorice, black and white pepper, paprika, coriander, saffron, and stevia tea. The active components of black pepper and chili pepper, piperine, and capsaicin exerted the highest transactivational activities with EC (50) values of 84 \u00b5M and 49 \u00b5M, respectively. The chalcones, including 2-hydroxychalcone, 2′-hydroxychalcone, 4-hydroxychalcone, and 4-methoxychalcone, moderately transactivated PPAR α. Resveratrol and apigenin only slightly transactivated PPAR α. These results suggest that a diet rich in fruit, herbs, and spices provides a number of PPAR α agonists that might contribute to an improved lipid profile.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-40059","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Christian Doppler Laboratory for Receptor Biotechnology, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.\r\n","annee":"2010","mois":"0","numero":"","page":"","auteurs":[{"ID":19036,"post_author":"0","post_date":"2018-12-03 20:15:50","post_date_gmt":"2018-12-03 19:15:50","post_content":"","post_title":"Haley V Becker","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"haley-v-becker","to_ping":"","pinged":"","post_modified":"2018-12-03 20:15:50","post_modified_gmt":"2018-12-03 19:15:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/haley-v-becker\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":19214,"post_author":"0","post_date":"2018-12-03 20:18:14","post_date_gmt":"2018-12-03 19:18:14","post_content":"","post_title":"Martina Mueller","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"martina-mueller","to_ping":"","pinged":"","post_modified":"2018-12-03 20:18:14","post_modified_gmt":"2018-12-03 19:18:14","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/martina-mueller\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":35584,"post_author":"0","post_date":"2018-12-04 00:46:21","post_date_gmt":"2018-12-03 23:46:21","post_content":"","post_title":"Jungbauer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jungbauer","to_ping":"","pinged":"","post_modified":"2018-12-04 00:46:21","post_modified_gmt":"2018-12-03 23:46:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jungbauer\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":11835,"post_author":"0","post_date":"2018-12-03 18:39:48","post_date_gmt":"2018-12-03 17:39:48","post_content":"","post_title":"PLANTA MEDICA","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"planta-medica","to_ping":"","pinged":"","post_modified":"2018-12-03 18:39:48","post_modified_gmt":"2018-12-03 17:39:48","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/planta-medica\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nPparα activation by culinary herbs and spices. - Aprifel<\/title>\n<meta name=\"description\" content=\"Pparα activation by culinary herbs and spices. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pparα activation by culinary herbs and spices.\" \/>\n<meta property=\"og:description\" content=\"Pparα activation by culinary herbs and spices.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/\",\"name\":\"Pparα activation by culinary herbs and spices. - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T01:08:05+00:00\",\"dateModified\":\"2018-12-04T01:08:05+00:00\",\"description\":\"Pparα activation by culinary herbs and spices. - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Pparα activation by culinary herbs and spices.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Pparα activation by culinary herbs and spices. - Aprifel","description":"Pparα activation by culinary herbs and spices. - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"Pparα activation by culinary herbs and spices.","og_description":"Pparα activation by culinary herbs and spices.","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/","name":"Pparα activation by culinary herbs and spices. - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T01:08:05+00:00","dateModified":"2018-12-04T01:08:05+00:00","description":"Pparα activation by culinary herbs and spices. - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/ppari-activation-by-culinary-herbs-and-spices\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"Pparα activation by culinary herbs and spices."}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/40059"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=40059"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=40059"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}