{"id":39980,"date":"2010-12-01T00:00:00","date_gmt":"2018-12-04T01:06:44","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/determination-of-new-biomarkers-to-monitor-the-dietary-consumption\/"},"modified":"2018-12-04T02:06:44","modified_gmt":"2018-12-04T01:06:44","slug":"determination-of-new-biomarkers-to-monitor-the-dietary-consumption","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/determination-of-new-biomarkers-to-monitor-the-dietary-consumption\/","title":{"rendered":"Determination of new biomarkers to monitor the dietary consumption of isothiocyanates."},"content":{"rendered":"<p>Isothiocyanates (ITCs) found in cruciferous vegetables have been associated with a reduced cancer risk in humans. We determined serum albumin adducts of allyl isothiocyanate (AITC), benzylisothiocyanate (BITC), phenylethylisothiocyanate (PEITC) and sulforaphane (SFN) in 85 healthy men from a dietary, randomized, controlled trial. After enzymatic digestion of albumin we determined the adducts of the ITCs with lysine (Lys) using liquid chromatography-tandem mass spectrometry. At the beginning of the study (and after 4 weeks) 4.7% (2.4%), 48.2% (35.3%), 5.9% (10.6%), and 24.7% (23.5%) of the samples were found positive for AITC-Lys, BITC-Lys, PEITC-Lys and SFN-Lys, respectively. This method enables the quantification of ITC adducts in albumin from large, prospective studies on diet and cancer.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-39980","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Tulane University School of Public Health, New Orleans, LA 70112, USA.\r\n","annee":"2010","mois":"12","numero":"15:8","page":"739-45","auteurs":[{"ID":13997,"post_author":"0","post_date":"2018-12-03 19:04:39","post_date_gmt":"2018-12-03 18:04:39","post_content":"","post_title":"Carlotta Sacerdote","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"carlotta-sacerdote","to_ping":"","pinged":"","post_modified":"2018-12-03 19:04:39","post_modified_gmt":"2018-12-03 18:04:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/carlotta-sacerdote\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":2877,"post_author":"0","post_date":"2018-12-03 17:00:03","post_date_gmt":"2018-12-03 16:00:03","post_content":"","post_title":"Paolo Vineis","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"paolo-vineis","to_ping":"","pinged":"","post_modified":"2018-12-03 17:00:03","post_modified_gmt":"2018-12-03 16:00:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/paolo-vineis\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":1201,"post_author":"0","post_date":"2018-12-03 15:57:16","post_date_gmt":"2018-12-03 14:57:16","post_content":"","post_title":"Ashish Kumar","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ashish-kumar","to_ping":"","pinged":"","post_modified":"2018-12-03 15:57:16","post_modified_gmt":"2018-12-03 14:57:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ashish-kumar\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":39979,"post_author":"0","post_date":"2018-12-04 02:06:44","post_date_gmt":"2018-12-04 01:06:44","post_content":"","post_title":"BIOMARKERS","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"biomarkers","to_ping":"","pinged":"","post_modified":"2018-12-04 02:06:44","post_modified_gmt":"2018-12-04 01:06:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/biomarkers\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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