{"id":39230,"date":"2011-03-01T00:00:00","date_gmt":"2018-12-04T00:51:57","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/principal-component-analysis-of-dietary-and-lifestyle-patterns\/"},"modified":"2018-12-04T01:51:57","modified_gmt":"2018-12-04T00:51:57","slug":"principal-component-analysis-of-dietary-and-lifestyle-patterns","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/principal-component-analysis-of-dietary-and-lifestyle-patterns\/","title":{"rendered":"Principal component analysis of dietary and lifestyle patterns in relation to risk of subtypes of esophageal and gastric cancer."},"content":{"rendered":"<p>PURPOSE:<\/p>\n<p>To carry out pattern analyses of dietary and lifestyle factors in relation to risk of esophageal and gastric cancers.<\/p>\n<p>METHODS:<\/p>\n<p>We evaluated risk factors for esophageal adenocarcinoma (EA), esophageal squamous cell carcinoma (ESCC), gastric cardia adenocarcinoma (GCA), and other gastric cancers (OGA) using data from a population-based case-control study conducted in Connecticut, New Jersey, and western Washington state. Dietary\/lifestyle patterns were created using principal component analysis (PCA). Impact of the resultant scores on cancer risk was estimated through logistic regression.<\/p>\n<p>RESULTS:<\/p>\n<p>PCA identified six patterns: meat\/nitrite, fruit\/vegetable, smoking\/alcohol, legume\/meat alternate, GERD\/BMI, and fish\/vitamin C. Risk of each cancer under study increased with rising meat\/nitrite score. Risk of EA increased with increasing GERD\/BMI score, and risk of ESCC rose with increasing smoking\/alcohol score and decreasing gastroesophageal reflux disease (GERD)\/body mass index (BMI) score. Fruit\/vegetable scores were inversely associated with EA, ESCC, and GCA.<\/p>\n<p>CONCLUSIONS:<\/p>\n<p>PCA may provide a useful approach for summarizing extensive dietary\/lifestyle data into fewer interpretable combinations that discriminate between cancer cases and controls. The analyses suggest that meat\/nitrite intake is associated with elevated risk of each cancer under study, whereas fruit\/vegetable intake reduces risk of EA, ESCC, and GCA. GERD\/obesity were confirmed as risk factors for EA and smoking\/alcohol as risk factors for ESCC.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-39230","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Montclair State University, Department of Health and Nutrition Sciences, Montclair, NJ","annee":"2011","mois":"3","numero":"","page":"","auteurs":[{"ID":29070,"post_author":"0","post_date":"2018-12-03 23:14:07","post_date_gmt":"2018-12-03 22:14:07","post_content":"","post_title":"S T Mayne","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"s-t-mayne","to_ping":"","pinged":"","post_modified":"2018-12-03 23:14:07","post_modified_gmt":"2018-12-03 22:14:07","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/s-t-mayne\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":29063,"post_author":"0","post_date":"2018-12-03 23:14:03","post_date_gmt":"2018-12-03 22:14:03","post_content":"","post_title":"Risch","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"risch","to_ping":"","pinged":"","post_modified":"2018-12-03 23:14:03","post_modified_gmt":"2018-12-03 22:14:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/risch\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":39229,"post_author":"0","post_date":"2018-12-04 01:51:56","post_date_gmt":"2018-12-04 00:51:56","post_content":"","post_title":"Navarro Silvera","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"navarro-silvera","to_ping":"","pinged":"","post_modified":"2018-12-04 01:51:56","post_modified_gmt":"2018-12-04 00:51:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/navarro-silvera\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":33432,"post_author":"0","post_date":"2018-12-04 00:12:55","post_date_gmt":"2018-12-03 23:12:55","post_content":"","post_title":"ANN EPIDEMIOL","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ann-epidemiol","to_ping":"","pinged":"","post_modified":"2018-12-04 00:12:55","post_modified_gmt":"2018-12-03 23:12:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/ann-epidemiol\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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