{"id":39147,"date":"2011-04-01T00:00:00","date_gmt":"2018-12-04T00:49:43","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/attenuation-of-meal-induced-inflammatory-and-thrombotic\/"},"modified":"2018-12-04T01:49:43","modified_gmt":"2018-12-04T00:49:43","slug":"attenuation-of-meal-induced-inflammatory-and-thrombotic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/attenuation-of-meal-induced-inflammatory-and-thrombotic\/","title":{"rendered":"Attenuation of meal-induced inflammatory and thrombotic responses in overweight men and women after 6-week daily strawberry (fragaria) intake."},"content":{"rendered":"<p>Aim: A pro-thrombotic, pro-inflammatory diet can play a causative role in atherosclerotic-cardiovascular diseases. Dietary intervention studies provide insight into their pathophysiological manifestations and opportunities for prevention and management. We previously showed in an acute-meal setting that a beverage containing polyphenolic- and antioxidant-rich strawberry (Fragaria) vs placebo attenuated postprandial (fed-state) increases in biomarkers of oxidative and inflammatory stress, and insulin concentrations, induced by a high carbohydrate\/fat (HCF) meal.In the present study, we aimed to extend our findings and investigate hypotheses related to the effects of chronic\/6-week (wk) strawberry consumption on HCF meal-induced increases in glucose, insulin, and indicators of inflammation and hemostasis.Methods: In a crossover design, 14 women and 10 men (mean age, BMI: 50.9\u00b115 years, 29.2\u00b12.3 kg\/m(2), respectively), were randomized to a 6-wk strawberry or placebo beverage followed by an HCF meal with assessments for 6-hours (h) postprandially.Results: HCF meal responses after 6-wk strawberry beverage showed significantly attenuated postprandial PAI-1 concentrations compared to the placebo (p =0.002); the difference was most notable at 6 h. The IL-1 &#946; response was attenuated with strawberry compared to the placebo (p =0.05). IL-6 attenuation was apparent but non-significant; IL-6 rose significantly from baseline to 6 h after the HCF meal following a placebo (p &#8804;0.01), although it remained relatively flat following the strawberry beverage from fasting to 6 h. No significant treatment-related differences were apparent for platelet aggregation, hsCRP, TNF-&#945;, insulin, or glucose.Conclusion: These data are the first to suggest that regular consumption of strawberry, a polyphenolic- and antioxidant-rich fruit, may provide protection from HCF meal-induced increases in fibrinolytic and inflammatory factors in at-risk men and women.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-39147","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Internal Medicine, Division of Cardiovascular Medicine, University of California-Davis.\r\n","annee":"2011","mois":"4","numero":"18:4","page":"318-327","auteurs":[{"ID":8527,"post_author":"0","post_date":"2018-12-03 18:01:10","post_date_gmt":"2018-12-03 17:01:10","post_content":"","post_title":"Indika Edirisinghe","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"indika-edirisinghe","to_ping":"","pinged":"","post_modified":"2018-12-03 18:01:10","post_modified_gmt":"2018-12-03 17:01:10","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/indika-edirisinghe\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7995,"post_author":"0","post_date":"2018-12-03 17:55:08","post_date_gmt":"2018-12-03 16:55:08","post_content":"","post_title":"Britt M Burton-freeman","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"britt-m-burton-freeman","to_ping":"","pinged":"","post_modified":"2018-12-03 17:55:08","post_modified_gmt":"2018-12-03 16:55:08","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/britt-m-burton-freeman\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":39145,"post_author":"0","post_date":"2018-12-04 01:49:42","post_date_gmt":"2018-12-04 00:49:42","post_content":"","post_title":"Ellis","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ellis-2","to_ping":"","pinged":"","post_modified":"2018-12-04 01:49:42","post_modified_gmt":"2018-12-04 00:49:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ellis-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":39146,"post_author":"0","post_date":"2018-12-04 01:49:43","post_date_gmt":"2018-12-04 00:49:43","post_content":"","post_title":"Kappagoda","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kappagoda","to_ping":"","pinged":"","post_modified":"2018-12-04 01:49:43","post_modified_gmt":"2018-12-04 00:49:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kappagoda\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":39003,"post_author":"0","post_date":"2018-12-04 01:46:29","post_date_gmt":"2018-12-04 00:46:29","post_content":"","post_title":"J ATHEROSCLER THROMB","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-atheroscler-thromb","to_ping":"","pinged":"","post_modified":"2018-12-04 01:46:29","post_modified_gmt":"2018-12-04 00:46:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/j-atheroscler-thromb\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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