BACKGROUND: Much research has been conducted relating total carotenoids–and β-carotene in particular–to risk of cancer and cardiovascular disease (CVD). Limited data are emerging to implicate the important role of α-carotene in the development of CVD or cancer.<\/p>\n
METHODS: We assessed the direct relationship between α-carotene concentrations and risk of death among 15,318 US adults 20 years and older who participated in the Third National Health and Nutrition Examination Survey Follow-up Study. We used Cox proportional hazard regression analyses to estimate the relative risk for death from all causes and selected causes associated with serum α-carotene concentrations.<\/p>\n
RESULTS: Compared with participants with serum α-carotene concentrations of 0 to 1 μg\/dL (to convert to micromoles per liter, multiply by 0.01863), those with higher serum levels had a lower risk of death from all causes (P < .001 for linear trend): the relative risk for death was 0.77 (95% confidence interval, 0.68-0.87) among those with α-carotene concentrations of 2 to 3 μg\/dL, 0.73 (0.65-0.83) among those with concentrations of 4 to 5 μg\/dL, 0.66 (0.55-0.79) among those with concentrations of 6 to 8 μg\/dL, and 0.61 (0.51-0.73) among those with concentrations of 9 μg\/dL or higher after adjustment for potential confounding variables. We also found significant associations between serum α-carotene concentrations and risk of death from CVD (P = .007), cancer (P = .02), and all other causes (P < .001). The association between serum α-carotene concentrations and risk of death from all causes was significant in most subgroups stratified by demographic characteristics, lifestyle habits, and health risk factors.<\/p>\n
CONCLUSIONS: Serum α-carotene concentrations were inversely associated with risk of death from all causes, CVD, cancer, and all other causes. These findings support increasing fruit and vegetable consumption as a means of preventing premature death<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-38635","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Division of Behavioral Surveillance, Office of Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS E97, Atlanta, GA 30333, USA","annee":"2011","mois":"3","numero":"171:6","page":"507-515","auteurs":[{"ID":37272,"post_author":"0","post_date":"2018-12-04 01:14:09","post_date_gmt":"2018-12-04 00:14:09","post_content":"","post_title":"Ford","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ford-2","to_ping":"","pinged":"","post_modified":"2018-12-04 01:14:09","post_modified_gmt":"2018-12-04 00:14:09","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ford-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":38590,"post_author":"0","post_date":"2018-12-04 01:39:54","post_date_gmt":"2018-12-04 00:39:54","post_content":"","post_title":"Hillier","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hillier","to_ping":"","pinged":"","post_modified":"2018-12-04 01:39:54","post_modified_gmt":"2018-12-04 00:39:54","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hillier\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":37915,"post_author":"0","post_date":"2018-12-04 01:26:29","post_date_gmt":"2018-12-04 00:26:29","post_content":"","post_title":"Balluz","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"balluz","to_ping":"","pinged":"","post_modified":"2018-12-04 01:26:29","post_modified_gmt":"2018-12-04 00:26:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/balluz\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":38222,"post_author":"0","post_date":"2018-12-04 01:33:51","post_date_gmt":"2018-12-04 00:33:51","post_content":"","post_title":"ARCH INTERN MED","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"arch-intern-med","to_ping":"","pinged":"","post_modified":"2018-12-04 01:33:51","post_modified_gmt":"2018-12-04 00:33:51","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/arch-intern-med\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n