{"id":38093,"date":"2012-04-01T00:00:00","date_gmt":"2018-12-04T00:30:38","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-flavonoid-intakes-and-risk-of-type-2-diabetes-in-us-men\/"},"modified":"2018-12-04T01:30:38","modified_gmt":"2018-12-04T00:30:38","slug":"dietary-flavonoid-intakes-and-risk-of-type-2-diabetes-in-us-men","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-flavonoid-intakes-and-risk-of-type-2-diabetes-in-us-men\/","title":{"rendered":"Dietary flavonoid intakes and risk of type 2 diabetes in US men and women."},"content":{"rendered":"<p style=\"text-align: justify\"><strong>BACKGROUND:<\/strong> Data from mechanistic studies support a beneficial effect of specific flavonoids on insulin sensitivity. However, few studies have evaluated the relation between intakes of different flavonoid subclasses and type 2 diabetes.<\/p>\n<p style=\"text-align: justify\"><strong>OBJECTIVE:<\/strong> The objective was to evaluate whether dietary intakes of major flavonoid subclasses (ie, flavonols, flavones, flavanones, flavan-3-ols, and anthocyanins) are associated with the risk of type 2 diabetes in US adults.<strong> <\/strong><\/p>\n<p style=\"text-align: justify\"><strong>DESIGN:<\/strong> We followed up a total of 70,359 women in the Nurses&#039; Health Study (NHS; 1984-2008), 89,201 women in the NHS II (1991-2007), and 41,334 men in the Health Professionals Follow-Up Study (1986-2006) who were free of diabetes, cardiovascular disease, and cancer at baseline.<\/p>\n<p style=\"text-align: justify\"><strong>RESULTS: <\/strong>During 3,645,585 person-years of follow-up, we documented 12,611 incident cases of type 2 diabetes. Higher intakes of anthocyanins were significantly associated with a lower risk of type 2 diabetes (pooled HR for the 3 cohorts from a comparison of extreme quintiles: 0.85; 95% CI: 0.80, 0.91; P-trend &lt; 0.001) after multivariate adjustment for age, BMI, and lifestyle and dietary factors. Consumption of anthocyanin-rich foods, particularly blueberries (pooled HR: 0.77 from a comparison of &ge;2 servings\/wk with &lt;1 serving\/mo; 95% CI: 0.68, 0.87; P-trend &lt; 0.001) and apples\/pears (pooled HR: 0.77 from a comparison of &ge;5 servings\/wk with &lt;1 serving\/mo; 95% CI: 0.65, 0.83; P-trend &lt; 0.001), was also associated with a lower risk of type 2 diabetes. No significant associations were found for total flavonoid intake or other flavonoid subclasses.<\/p>\n<p style=\"text-align: justify\"><strong>CONCLUSION: <\/strong>A higher consumption of anthocyanins and anthocyanin-rich fruit was associated with a lower risk of type 2 diabetes.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-38093","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Departments of Nutrition, Harvard School of Public Health, Boston, MA; Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.\r\n","annee":"2012","mois":"4","numero":"95:4","page":"925-933","auteurs":[{"ID":5045,"post_author":"0","post_date":"2018-12-03 17:23:41","post_date_gmt":"2018-12-03 16:23:41","post_content":"","post_title":"Aedin Cassidy","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"aedin-cassidy","to_ping":"","pinged":"","post_modified":"2018-12-03 17:23:41","post_modified_gmt":"2018-12-03 16:23:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/aedin-cassidy\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":30877,"post_author":"0","post_date":"2018-12-03 23:37:43","post_date_gmt":"2018-12-03 22:37:43","post_content":"","post_title":"Nicole M Wedick","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nicole-m-wedick","to_ping":"","pinged":"","post_modified":"2018-12-03 23:37:43","post_modified_gmt":"2018-12-03 22:37:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/nicole-m-wedick\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":24374,"post_author":"0","post_date":"2018-12-03 21:52:11","post_date_gmt":"2018-12-03 20:52:11","post_content":"","post_title":"Anand Pandit","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"anand-pandit","to_ping":"","pinged":"","post_modified":"2018-12-03 21:52:11","post_modified_gmt":"2018-12-03 20:52:11","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/anand-pandit\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1720,"post_author":"0","post_date":"2018-12-03 16:01:56","post_date_gmt":"2018-12-03 15:01:56","post_content":"","post_title":"Am J Clin Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-clin-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:56","post_modified_gmt":"2018-12-03 15:01:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-clin-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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