BACKGROUND: Dietary intake is known to influence glucose metabolism, but there is little consensus on the optimal distribution of macronutrient intakes during pregnancy to prevent gestational diabetes (GDM).<\/p>\n
OBJECTIVE: We aimed to investigate whether macronutrient intake distribution during the second trimester of pregnancy was associated with glucose metabolism later in pregnancy.<\/p>\n
DESIGN: Women with singleton pregnancies and without preexisting type 1 or type 2 diabetes were included. Participants underwent a 3-h oral-glucose-tolerance test at 30 wk (95% CI: 25, 33 wk) gestation and were asked to recall their second-trimester dietary intake by using a validated food-frequency questionnaire.<\/p>\n
RESULTS: Of the 205 participants, 47 (22.9%) had a diagnosis of GDM. A higher intake of saturated fat (β \u00b1 SEE: 0.059 \u00b1 0.021; P = 0.005) and trans fat (0.381 \u00b1 0.145; P = 0.009) as a percentage of energy and of added sugar (0.017 \u00b1 0.007; P = 0.02) and a lower intake of vegetable and fruit fiber (-0.026 \u00b1 0.012; P = 0.03) were individually associated with increased fasting glucose after multiple adjustment. In participants with a family history of type 2 diabetes, a higher vegetable and fruit fiber intake was associated with reduced insulin resistance (-0.100 \u00b1 0.029; P = 0.0008) and increased insulin sensitivity (0.029 \u00b1 0.012; P = 0.01), after similar adjustment. An increased risk (OR per 1-SD change) of GDM was associated with lower carbohydrate (0.60; 95% CI: 0.40, 0.90) and higher total fat (1.61; 95% CI: 1.06, 2.44) intakes as a percentage of energy, after similar adjustment.<\/p>\n
CONCLUSIONS: Macronutrient intake during the second trimester of pregnancy was associated with a risk of abnormal glucose metabolism later in pregnancy. This finding supports the need for continued work to determine optimal prenatal nutritional strategies to prevent GDM. <\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-37873","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Nutritional Sciences, Mount Sinai Hospital, Toronto, Canada.\r\n","annee":"2011","mois":"11","numero":"94:5","page":"1232-1240","auteurs":[{"ID":22490,"post_author":"0","post_date":"2018-12-03 21:05:32","post_date_gmt":"2018-12-03 20:05:32","post_content":"","post_title":"Sylvia H Ley","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sylvia-h-ley","to_ping":"","pinged":"","post_modified":"2018-12-03 21:05:32","post_modified_gmt":"2018-12-03 20:05:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sylvia-h-ley\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":12778,"post_author":"0","post_date":"2018-12-03 18:50:22","post_date_gmt":"2018-12-03 17:50:22","post_content":"","post_title":"Anthony J Hanley","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"anthony-j-hanley","to_ping":"","pinged":"","post_modified":"2018-12-03 18:50:22","post_modified_gmt":"2018-12-03 17:50:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/anthony-j-hanley\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":37872,"post_author":"0","post_date":"2018-12-04 01:25:28","post_date_gmt":"2018-12-04 00:25:28","post_content":"","post_title":"Retnakaran","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"retnakaran","to_ping":"","pinged":"","post_modified":"2018-12-04 01:25:28","post_modified_gmt":"2018-12-04 00:25:28","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/retnakaran\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1720,"post_author":"0","post_date":"2018-12-03 16:01:56","post_date_gmt":"2018-12-03 15:01:56","post_content":"","post_title":"Am J Clin Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-clin-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:56","post_modified_gmt":"2018-12-03 15:01:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-clin-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n