{"id":37752,"date":"2011-12-01T00:00:00","date_gmt":"2018-12-04T00:22:36","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/adolescent-and-mid-life-diet-risk-of-colorectal-cancer-in\/"},"modified":"2018-12-04T01:22:36","modified_gmt":"2018-12-04T00:22:36","slug":"adolescent-and-mid-life-diet-risk-of-colorectal-cancer-in","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/adolescent-and-mid-life-diet-risk-of-colorectal-cancer-in\/","title":{"rendered":"Adolescent and mid-life diet: risk of colorectal cancer in the NIH-AARP Diet and Health Study."},"content":{"rendered":"

BACKGROUND:<\/strong>
\nColorectal cancer has a natural history of several decades; therefore, the diet consumed decades before diagnosis may aid in understanding this malignancy.<\/p>\n

OBJECTIVE:<\/strong>
\nThe objective was to investigate diet during adolescence and 10 y before baseline (ages 40-61 y) in relation to colorectal cancer.<\/p>\n

DESIGN:<\/strong>
\nParticipants in the NIH-AARP Diet and Health Study (n = 292,797) completed a 124-item food-frequency questionnaire (FFQ) about diet in the past 12 mo and two 37-item FFQs about diet at ages 12-13 y and 10 y previously. Cox regression was used to estimate multivariate HRs and 95% CIs for colon (n = 2794) and rectal (n = 979) cancers within quintiles of exposures.<\/p>\n

RESULTS:<\/strong>
\nColon cancer risk was lower in the highest than in the lowest quintile of vitamin A (HR: 0.82; 95% CI: 0.72, 0.92) and vegetable (HR: 0.81, 0.70, 0.92) intakes during adolescence. Those in the highest intake category 10 y previously for calcium (HR: 0.83; 95% CI: 0.73, 0.94), vitamin A (HR: 0.81; 95% CI: 0.71, 0.92), vitamin C (HR: 0.83; 95% CI: 0.72, 0.95), fruit (HR: 0.84; 95% CI: 0.73, 0.97), and milk (HR: 0.78; 95% CI: 0.67, 0.90) had a lower risk of colon cancer, but a higher risk was observed for total fat (HR: 1.15; 95% CI: 1.01, 1.30), red meat (HR: 1.31; 95% CI: 1.12, 1.53), and processed meat (HR: 1.24; 95% CI: 1.06, 1.45). For rectal cancer, milk was inversely associated (HR: 0.75; 95% CI: 0.58, 0.96) with risk.<\/p>\n

CONCLUSION:<\/strong>
\nAdolescent and midlife diet may play a role in colorectal carcinogenesis.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-37752","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA","annee":"2011","mois":"12","numero":"94:6","page":"1607-1619","auteurs":[{"ID":14578,"post_author":"0","post_date":"2018-12-03 19:11:24","post_date_gmt":"2018-12-03 18:11:24","post_content":"","post_title":"Frances E Thompson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"frances-e-thompson","to_ping":"","pinged":"","post_modified":"2018-12-03 19:11:24","post_modified_gmt":"2018-12-03 18:11:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/frances-e-thompson\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":37750,"post_author":"0","post_date":"2018-12-04 01:22:34","post_date_gmt":"2018-12-04 00:22:34","post_content":"","post_title":"Ruder","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ruder","to_ping":"","pinged":"","post_modified":"2018-12-04 01:22:34","post_modified_gmt":"2018-12-04 00:22:34","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ruder\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":37751,"post_author":"0","post_date":"2018-12-04 01:22:35","post_date_gmt":"2018-12-04 00:22:35","post_content":"","post_title":"Thiebaut","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"thiebaut","to_ping":"","pinged":"","post_modified":"2018-12-04 01:22:35","post_modified_gmt":"2018-12-04 00:22:35","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/thiebaut\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1720,"post_author":"0","post_date":"2018-12-03 16:01:56","post_date_gmt":"2018-12-03 15:01:56","post_content":"","post_title":"Am J Clin Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-clin-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:56","post_modified_gmt":"2018-12-03 15:01:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-clin-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nAdolescent and mid-life diet: risk of colorectal cancer in the NIH-AARP Diet and Health Study. - 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