{"id":37033,"date":"2012-03-01T00:00:00","date_gmt":"2018-12-04T00:10:22","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/derivation-and-validation-of-a-prediction-rule-for-estimating\/"},"modified":"2018-12-04T01:10:22","modified_gmt":"2018-12-04T00:10:22","slug":"derivation-and-validation-of-a-prediction-rule-for-estimating","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/derivation-and-validation-of-a-prediction-rule-for-estimating\/","title":{"rendered":"Derivation and validation of a prediction rule for estimating advanced colorectal neoplasm risk in average-risk Chinese"},"content":{"rendered":"<p style=\"text-align: justify\">No prediction rule is currently available for advanced colorectal neoplasms, defined as invasive cancer, an adenoma of 10 mm or more, a villous adenoma, or an adenoma with high-grade dysplasia, in average-risk Chinese. In this study between 2006 and 2008, a total of 7,541 average-risk Chinese persons aged 40 years or older who had complete colonoscopy were included. The derivation and validation cohorts consisted of 5,229 and 2,312 persons, respectively. A prediction rule was developed from a logistic regression model and then internally and externally validated. The prediction rule comprised 8 variables (age, sex, smoking, diabetes mellitus, green vegetables, pickled food, fried food, and white meat), with scores ranging from 0 to 14. Among the participants with low-risk (&le;3) or high-risk (&gt;3) scores in the validation cohort, the risks of advanced neoplasms were 2.6% and 10.0% (P &lt; 0.001), respectively. If colonoscopy was used only for persons with high risk, 80.3% of persons with advanced neoplasms would be detected while the number of colonoscopies would be reduced by 49.2%. The prediction rule had good discrimination (area under the receiver operating characteristic curve = 0.74, 95% confidence interval: 0.70, 0.78) and calibration (P = 0.77) and, thus, provides accurate risk stratification for advanced neoplasms in average-risk Chinese.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-37033","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China","annee":"2012","mois":"3","numero":"175:6","page":"584-593","auteurs":[{"ID":1677,"post_author":"0","post_date":"2018-12-03 16:01:33","post_date_gmt":"2018-12-03 15:01:33","post_content":"","post_title":"Ying Xiao","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ying-xiao","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:33","post_modified_gmt":"2018-12-03 15:01:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ying-xiao\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":37031,"post_author":"0","post_date":"2018-12-04 01:10:21","post_date_gmt":"2018-12-04 00:10:21","post_content":"","post_title":"Cai","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"cai","to_ping":"","pinged":"","post_modified":"2018-12-04 01:10:21","post_modified_gmt":"2018-12-04 00:10:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/cai\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":37032,"post_author":"0","post_date":"2018-12-04 01:10:21","post_date_gmt":"2018-12-04 00:10:21","post_content":"","post_title":"Yu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"yu","to_ping":"","pinged":"","post_modified":"2018-12-04 01:10:21","post_modified_gmt":"2018-12-04 00:10:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/yu\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":36097,"post_author":"0","post_date":"2018-12-04 00:54:26","post_date_gmt":"2018-12-03 23:54:26","post_content":"","post_title":"Am J Epidemiol.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-epidemiol","to_ping":"","pinged":"","post_modified":"2018-12-04 00:54:26","post_modified_gmt":"2018-12-03 23:54:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-epidemiol\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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