{"id":36622,"date":"2012-04-01T00:00:00","date_gmt":"2018-12-04T00:03:59","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-mediterranean-diets-on-kidney-function-a-report\/"},"modified":"2018-12-04T01:03:59","modified_gmt":"2018-12-04T00:03:59","slug":"effects-of-mediterranean-diets-on-kidney-function-a-report","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-mediterranean-diets-on-kidney-function-a-report\/","title":{"rendered":"Effects of mediterranean diets on kidney function: a report from the predimed trial"},"content":{"rendered":"<p><strong>BACKGROUND<\/strong>: Epidemiologic observations have linked healthy dietary patterns to improved kidney function.<\/p>\n<p><strong>STUDY DESIGN<\/strong>: We assessed the effects of the Mediterranean diet (MedDiet) on kidney function in both a cross-sectional assessment and after a 1-year intervention in a cohort of the PREDIMED (Prevenci&oacute;n con Dieta Mediterr&aacute;nea) Study, a multicenter 3-arm randomized clinical trial to determine the efficacy of the MedDiet on primary cardiovascular prevention.<\/p>\n<p><strong>SETTING &amp; PARTICIPANTS<\/strong>: Community-dwelling men aged 55-80 years and women aged 60-80 years at high risk of cardiovascular disease from Reus, Spain.<\/p>\n<p><strong>INTERVENTION<\/strong>: Participants were randomly assigned to 3 ad libitum diets: a MedDiet supplemented with virgin olive oil (MedDiet + olive oil), a MedDiet supplemented with mixed nuts (MedDiet + nuts), or a control low-fat diet.<\/p>\n<p><strong>OUTCOMES<\/strong>: Estimated glomerular filtration rate (eGFR) and urinary albumin-creatinine ratio (ACR).<\/p>\n<p><strong>MEASUREMENTS<\/strong>: Nutrient intake, adherence to the MedDiet, lifestyle variables, cardiovascular risk factors, serum urea and creatinine concentrations, eGFR, and urinary ACR were evaluated at baseline and after intervention for 1 year.<\/p>\n<p><strong>RESULTS<\/strong>: Baseline kidney function markers were similar across quartiles of adherence to the MedDiet in 785 participants (55% women; mean age, 67 years). After a 1-year intervention in 665 participants, the 3 dietary approaches were associated with improved kidney function, with similar average increases in eGFR (4.7 [95% CI, 3.2-6.2], 3.5 [95% CI, 1.9-5.0], and 4.1 [95% CI, 2.8-5.5] mL\/min\/1.73 m(2) for the MedDiet + olive oil, MedDiet + nuts, and control groups, respectively [P &lt; 0.001 vs baseline for each; P = 0.9 for differences among groups]), but no changes in ACRs after adjustment for various confounders.<\/p>\n<p><strong>LIMITATIONS<\/strong>: Generalization of results to other age groups or ethnicities. GFR was not directly measured.<\/p>\n<p><strong>CONCLUSIONS<\/strong>: The results do not support the notion that the MedDiet has a beneficial effect on kidney function over and above that of advice for a low-fat diet in elderly individuals at high cardiovascular risk.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-36622","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Human Nutrition Unit, Faculty of Medicine and Health Sciences, IISPV, Universitat Rovira i Virgili, Reus, Tarragona, Spain","annee":"2012","mois":"4","numero":"60:3","page":"380-389","auteurs":[{"ID":1549,"post_author":"0","post_date":"2018-12-03 16:00:25","post_date_gmt":"2018-12-03 15:00:25","post_content":"","post_title":"Miguel Angel Mart\u00ednez-Gonz\u00e1lez","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"miguel-angel-martinez-gonzalez","to_ping":"","pinged":"","post_modified":"2018-12-03 16:00:25","post_modified_gmt":"2018-12-03 15:00:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/miguel-angel-martinez-gonzalez\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":5350,"post_author":"0","post_date":"2018-12-03 17:26:56","post_date_gmt":"2018-12-03 16:26:56","post_content":"","post_title":"M\u00f2nica Bull\u00f3","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"monica-bullo","to_ping":"","pinged":"","post_modified":"2018-12-03 17:26:56","post_modified_gmt":"2018-12-03 16:26:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/monica-bullo\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":4551,"post_author":"0","post_date":"2018-12-03 17:18:33","post_date_gmt":"2018-12-03 16:18:33","post_content":"","post_title":"Andr\u00e9s D\u00edaz-L\u00f3pez","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"andres-diaz-lopez","to_ping":"","pinged":"","post_modified":"2018-12-03 17:18:33","post_modified_gmt":"2018-12-03 16:18:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/andres-diaz-lopez\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":36621,"post_author":"0","post_date":"2018-12-04 01:03:58","post_date_gmt":"2018-12-04 00:03:58","post_content":"","post_title":"AM J KIDNEY DIS.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-kidney-dis","to_ping":"","pinged":"","post_modified":"2018-12-04 01:03:58","post_modified_gmt":"2018-12-04 00:03:58","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-kidney-dis\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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