{"id":36236,"date":"2012-04-01T00:00:00","date_gmt":"2018-12-03T23:56:43","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-mediterranean-diet-pattern-and-its-main-components-are\/"},"modified":"2018-12-04T00:56:43","modified_gmt":"2018-12-03T23:56:43","slug":"the-mediterranean-diet-pattern-and-its-main-components-are","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-mediterranean-diet-pattern-and-its-main-components-are\/","title":{"rendered":"The mediterranean diet pattern and its main components are associated with lower plasma concentrations of tumor necrosis factor receptor 60 in patients at high risk for cardiovascular disease"},"content":{"rendered":"<p style=\"text-align: justify\">Adherence to a Mediterranean diet (MD) is associated with a reduced risk of coronary heart disease. However, the molecular mechanisms involved are not fully understood. The aim of this study was to compare the effects of 2 MD with those of a low-fat-diet (LFD) on circulating inflammatory biomarkers related to atherogenesis. A total of 516 participants included in the Prevention with Mediterranean Diet Study were randomized into 3 intervention groups [MD supplemented with virgin olive oil (MD-VOO); MD supplemented with mixed nuts (MD-Nuts); and LFD]. At baseline and after 1 y, participants completed FFQ and adherence to MD questionnaires, and plasma concentrations of inflammatory markers including intercellular adhesion molecule-1(ICAM-1), IL-6, and 2 TNF receptors (TNFR60 and TNFR80) were measured by ELISA. At 1 y, the MD groups had lower plasma concentrations of IL-6, TNFR60, and TNFR80 (P &lt; 0.05), whereas ICAM-1, TNFR60, and TNFR80 concentrations increased in the LFD group (P &lt; 0.002). Due to between-group differences, participants in the 2 MD groups had lower plasma concentrations of ICAM-1, IL-6, TNFR60, and TNFR80 compared to those in the LFD group (P &le; 0.028). When participants were categorized in tertiles of 1-y changes in the consumption of selected foods, those in the highest tertile of virgin olive oil (VOO) and vegetable consumption had a lower plasma TNFR60 concentration compared with those in tertile 1 (P &lt; 0.02). Moreover, the only changes in consumption that were associated with 1-y changes in the geometric mean TNFR60 concentrations were those of VOO and vegetables (P = 0.01). This study suggests that a MD reduces TNFR concentrations in patients at high cardiovascular risk.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-36236","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Internal Medicine, University of Barcelona, Barcelona, Spain.\r\n\r\n","annee":"2012","mois":"4","numero":"142:6","page":"1019-1025","auteurs":[{"ID":18484,"post_author":"0","post_date":"2018-12-03 20:07:37","post_date_gmt":"2018-12-03 19:07:37","post_content":"","post_title":"Mireia Urp\u00ed-Sard\u00e0","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mireia-urpi-sarda","to_ping":"","pinged":"","post_modified":"2018-12-03 20:07:37","post_modified_gmt":"2018-12-03 19:07:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mireia-urpi-sarda\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":18482,"post_author":"0","post_date":"2018-12-03 20:07:33","post_date_gmt":"2018-12-03 19:07:33","post_content":"","post_title":"Rosa Casas","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rosa-casas","to_ping":"","pinged":"","post_modified":"2018-12-03 20:07:33","post_modified_gmt":"2018-12-03 19:07:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/rosa-casas\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":11975,"post_author":"0","post_date":"2018-12-03 18:41:22","post_date_gmt":"2018-12-03 17:41:22","post_content":"","post_title":"Gemma Chiva-Blanch","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"gemma-chiva-blanch","to_ping":"","pinged":"","post_modified":"2018-12-03 18:41:22","post_modified_gmt":"2018-12-03 17:41:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/gemma-chiva-blanch\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":32402,"post_author":"0","post_date":"2018-12-03 23:58:36","post_date_gmt":"2018-12-03 22:58:36","post_content":"","post_title":"J NUTR","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-nutr-2","to_ping":"","pinged":"","post_modified":"2018-12-03 23:58:36","post_modified_gmt":"2018-12-03 22:58:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/j-nutr-2\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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