{"id":36094,"date":"2012-08-01T00:00:00","date_gmt":"2018-12-03T23:54:22","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-consumption-and-risk-of-aggressive-and\/"},"modified":"2018-12-04T00:54:22","modified_gmt":"2018-12-03T23:54:22","slug":"fruit-and-vegetable-consumption-and-risk-of-aggressive-and","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-consumption-and-risk-of-aggressive-and\/","title":{"rendered":"Fruit and vegetable consumption and risk of aggressive and non-aggressive urothelial cell carcinomas in the european prospective investigation into cancer and nutrition."},"content":{"rendered":"<p>BACKGROUND: <\/p>\n<p>Many epidemiological studies have examined fruit and vegetable consumption in relation to the risk of urothelial cell carcinoma (UCC) of the bladder, but results are inconsistent. The association between fruit and vegetable consumption and UCC risk may vary by bladder tumour aggressiveness. Therefore, we examined the relation between fruit and vegetable consumption and the risk of aggressive and non-aggressive UCC in the European Prospective Investigation into Cancer and Nutrition (<span class='tooltipsall tooltip_post_id_80438 classtoolTips80438'>EPIC<\/span>).<\/p>\n<p>METHODS: <\/p>\n<p>After 8.9years of follow-up, 947UCC were diagnosed among 468,656 <span class='tooltipsall tooltip_post_id_80438 classtoolTips80438'>EPIC<\/span> participants. Of these, 421 could be classified as aggressive UCC and 433 as non-aggressive UCC cases. At recruitment, fruit and vegetable consumption was assessed by validated dietary questionnaires. Multivariable hazard ratios were estimated using Cox regression stratified by age, sex and center and adjusted for smoking status, duration and intensity of smoking, and energy intake.<\/p>\n<p>RESULTS: <\/p>\n<p>Total consumption of fruits and vegetables was not associated with aggressive UCC nor with non-aggressive UCC. A 25g\/day increase in leafy vegetables and grapes consumption was associated with a reduced risk of non-aggressive UCC (hazard ratio (HR) 0.88; 95%confidence interval (CI) 0.78-1.00 and HR 0.87; 95%CI 0.77-0.98, respectively), while the intake of root vegetables was inversely associated with risk of aggressive UCC (HR 0.87; 95%CI 0.77-0.98).<\/p>\n<p>CONCLUSION: <\/p>\n<p>Our study did not confirm a protective effect of total fruit and\/or vegetable consumption on aggressive or non-aggressive UCC. High consumption of certain types of vegetables and of fruits may reduce the risk of aggressive or non-aggressive UCC; however chance findings cannot be excluded.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-36094","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands","annee":"2012","mois":"8","numero":"48:17","page":"3267-3277","auteurs":[{"ID":36091,"post_author":"0","post_date":"2018-12-04 00:54:20","post_date_gmt":"2018-12-03 23:54:20","post_content":"","post_title":"Martine M Ros","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"martine-m-ros","to_ping":"","pinged":"","post_modified":"2018-12-04 00:54:20","post_modified_gmt":"2018-12-03 23:54:20","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/martine-m-ros\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":13170,"post_author":"0","post_date":"2018-12-03 18:55:03","post_date_gmt":"2018-12-03 17:55:03","post_content":"","post_title":"Ellen Kampman","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ellen-kampman","to_ping":"","pinged":"","post_modified":"2018-12-03 18:55:03","post_modified_gmt":"2018-12-03 17:55:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ellen-kampman\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":36092,"post_author":"0","post_date":"2018-12-04 00:54:21","post_date_gmt":"2018-12-03 23:54:21","post_content":"","post_title":"Bas Bueno-de-mesquita","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bas-bueno-de-mesquita","to_ping":"","pinged":"","post_modified":"2018-12-04 00:54:21","post_modified_gmt":"2018-12-03 23:54:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bas-bueno-de-mesquita\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":36093,"post_author":"0","post_date":"2018-12-04 00:54:21","post_date_gmt":"2018-12-03 23:54:21","post_content":"","post_title":"EUR J CANCER","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"eur-j-cancer","to_ping":"","pinged":"","post_modified":"2018-12-04 00:54:21","post_modified_gmt":"2018-12-03 23:54:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/eur-j-cancer\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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