{"id":35325,"date":"2012-12-01T00:00:00","date_gmt":"2018-12-03T23:42:25","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/"},"modified":"2018-12-04T00:42:25","modified_gmt":"2018-12-03T23:42:25","slug":"cancer-prevention-with-promising-natural-products-mechanisms","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/","title":{"rendered":"Cancer prevention with promising natural products: mechanisms of action and molecular targets."},"content":{"rendered":"<p>Cancer is the second leading cause of death worldwide. There is greater need for more effective and less toxic therapeutic and preventive strategies. Natural products are becoming an important research area for novel and bioactive molecules for drug discovery. Phytochemicals and dietary compounds have been used for the treatment of cancer throughout history due to their safety, low toxicity, and general availability. Many active phytochemicals are in human clinical trials. Studies have indicated that daily consumption of dietary phytochemicals have cancer protective effects against carcinogens. They can inhibit, delay, or reverse carcinogenesis by inducing detoxifying and antioxidant enzymes systems, regulating inflammatory and proliferative signaling pathways, and inducing cell cycle arrest and apoptosis. Epidemiological studies have also revealed that high dietary intakes of fruits and vegetables reduce the risk of cancer. This review discusses potential natural cancer preventive compounds, their molecular targets, and their mechanisms of actions.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-35325","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40536, USA.","annee":"2012","mois":"12","numero":"12:10","page":"1159-1184","auteurs":[{"ID":16046,"post_author":"0","post_date":"2018-12-03 19:34:03","post_date_gmt":"2018-12-03 18:34:03","post_content":"","post_title":"Zuo-Feng Zhang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"zuo-feng-zhang","to_ping":"","pinged":"","post_modified":"2018-12-03 19:34:03","post_modified_gmt":"2018-12-03 18:34:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/zuo-feng-zhang\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":35322,"post_author":"0","post_date":"2018-12-04 00:42:24","post_date_gmt":"2018-12-03 23:42:24","post_content":"","post_title":"Pratheeshkumar","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"pratheeshkumar","to_ping":"","pinged":"","post_modified":"2018-12-04 00:42:24","post_modified_gmt":"2018-12-03 23:42:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/pratheeshkumar\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":35323,"post_author":"0","post_date":"2018-12-04 00:42:25","post_date_gmt":"2018-12-03 23:42:25","post_content":"","post_title":"Sreekala","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sreekala","to_ping":"","pinged":"","post_modified":"2018-12-04 00:42:25","post_modified_gmt":"2018-12-03 23:42:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sreekala\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":35324,"post_author":"0","post_date":"2018-12-04 00:42:25","post_date_gmt":"2018-12-03 23:42:25","post_content":"","post_title":"Anticancer Agents Med Chem.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"anticancer-agents-med-chem","to_ping":"","pinged":"","post_modified":"2018-12-04 00:42:25","post_modified_gmt":"2018-12-03 23:42:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/anticancer-agents-med-chem\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel<\/title>\n<meta name=\"description\" content=\"Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cancer prevention with promising natural products: mechanisms of action and molecular targets.\" \/>\n<meta property=\"og:description\" content=\"Cancer prevention with promising natural products: mechanisms of action and molecular targets.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/\",\"name\":\"Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-03T23:42:25+00:00\",\"dateModified\":\"2018-12-03T23:42:25+00:00\",\"description\":\"Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Cancer prevention with promising natural products: mechanisms of action and molecular targets.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel","description":"Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"Cancer prevention with promising natural products: mechanisms of action and molecular targets.","og_description":"Cancer prevention with promising natural products: mechanisms of action and molecular targets.","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/","name":"Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-03T23:42:25+00:00","dateModified":"2018-12-03T23:42:25+00:00","description":"Cancer prevention with promising natural products: mechanisms of action and molecular targets. - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/cancer-prevention-with-promising-natural-products-mechanisms\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"Cancer prevention with promising natural products: mechanisms of action and molecular targets."}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/35325"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=35325"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=35325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}