{"id":34845,"date":"2013-04-01T00:00:00","date_gmt":"2018-12-03T23:35:37","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/nutrient-intake-and-nutrient-patterns-and-risk-of-lung-cancer\/"},"modified":"2018-12-04T00:35:37","modified_gmt":"2018-12-03T23:35:37","slug":"nutrient-intake-and-nutrient-patterns-and-risk-of-lung-cancer","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/nutrient-intake-and-nutrient-patterns-and-risk-of-lung-cancer\/","title":{"rendered":"Nutrient intake and nutrient patterns and risk of lung cancer among heavy smokers: results from the cosmos screening study with annual low-dose ct."},"content":{"rendered":"<p>The role of nutrients in lung cancer aetiology remains controversial and has never been evaluated in the context of screening. Our aim was to investigate the role of single nutrients and nutrient patterns in the aetiology of lung cancer in heavy smokers. Asymptomatic heavy smokers (&#8805;20 pack-years) were invited to undergo annual low-dose computed tomography. We assessed diet using a self-administered food frequency questionnaire and collected information on multivitamin supplement use. We performed principal component analysis identifying four nutrient patterns and used Cox proportional Hazards regression to assess the association between nutrients and nutrients patterns and lung cancer risk. During a mean follow-up of 5.7 years, 178 of 4,336 participants were diagnosed with lung cancer by screening. We found a significant risk reduction of lung cancer with increasing vegetable fat consumption (HR for highest vs. lowest quartile = 0.50, 95 % CI = 0.31-0.80; P-trend = 0.02). Participants classified in the high \u00ab\u00a0vitamins and fiber\u00a0\u00bb pattern score had a significant risk reduction of lung cancer (HR = 0.57; 95 % CI = 0.36-0.90, P-trend = 0.01). Among heavy smokers enrolled in a screening trial, high vegetable fat intake and adherence to the \u00ab\u00a0vitamin and fiber\u00a0\u00bb nutrient pattern were associated with reduced lung cancer incidence.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-34845","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ramusio 1, Milan, 20141, Italy, patrizia.gnagnarella@ieo.it.","annee":"2013","mois":"4","numero":"","page":"","auteurs":[{"ID":34843,"post_author":"0","post_date":"2018-12-04 00:35:36","post_date_gmt":"2018-12-03 23:35:36","post_content":"","post_title":"Gnagnarella","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"gnagnarella","to_ping":"","pinged":"","post_modified":"2018-12-04 00:35:36","post_modified_gmt":"2018-12-03 23:35:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/gnagnarella\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":29840,"post_author":"0","post_date":"2018-12-03 23:24:21","post_date_gmt":"2018-12-03 22:24:21","post_content":"","post_title":"Patrick Maisonneuve","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"patrick-maisonneuve","to_ping":"","pinged":"","post_modified":"2018-12-03 23:24:21","post_modified_gmt":"2018-12-03 22:24:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/patrick-maisonneuve\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":34844,"post_author":"0","post_date":"2018-12-04 00:35:37","post_date_gmt":"2018-12-03 23:35:37","post_content":"","post_title":"Bellomi","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bellomi","to_ping":"","pinged":"","post_modified":"2018-12-04 00:35:37","post_modified_gmt":"2018-12-03 23:35:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bellomi\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":31483,"post_author":"0","post_date":"2018-12-03 23:45:43","post_date_gmt":"2018-12-03 22:45:43","post_content":"","post_title":"Eur J Epidemiol.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"eur-j-epidemiol","to_ping":"","pinged":"","post_modified":"2018-12-03 23:45:43","post_modified_gmt":"2018-12-03 22:45:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/eur-j-epidemiol\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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