OBJECTIVE: In short-term feeding trials, replacement of other macronutrients with monounsaturated fatty acid reduces blood pressure. However, observational studies have not clearly demonstrated a relationship between monounsaturated fatty acid intake and blood pressure. We report associations of monounsaturated fatty acid intake of individuals with blood pressure in a cross-sectional study.<\/p>\n
METHODS: The International Study of Macro\/Micronutrients and Blood Pressure is a cross-sectional epidemiologic study of 4680 men and women ages 40-59 years from 17 population samples in China, Japan, UK and USA. Nutrient intake data were based on four in-depth multipass 24-h dietary recalls\/person and two-timed 24-h urine collections\/person. Blood pressure was measured eight times at four visits.<\/p>\n
RESULTS: Mean monounsaturated fatty acid intake ranged from 8.1%kcal (China) to 12.2%kcal (USA). With sequential models to control for possible confounders (dietary, other), linear regression analyses showed significant inverse relationship of total monounsaturated fatty acid intake with DBP for all participants; for 2238 'nonintervened' individuals, the relationship was stronger. Estimated DBP differences with 2-SD higher monounsaturated fatty acids (5.35%kcal) were -0.82 mmHg (P < 0.05) for all participants and -1.70 mmHg (P < 0.01) for nonintervened individuals. Inverse associations of dietary total oleic acid (main monounsaturated) with blood pressure in nonintervened individuals were not significant, but those of oleic acid from vegetable sources were stronger and significant (P < 0.05).<\/p>\n
CONCLUSION: Dietary monounsaturated fatty acid intake, especially oleic acid from vegetable sources, may contribute to prevention and control of adverse blood pressure levels in general populations.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-34692","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"aDepartment of Health Science, Shiga University of Medical Science, Otsu, Japan bDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA cDepartment of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK dDepartment of Epidemiology and Public Health, Kanazawa Medical University, Ishikawa, Japan eWelch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA fFirst Institute of Health Service, Japan Anti-Tuberculosis Association gDepartment of Nutritional Education, National Institute of Health and Nutrition, Tokyo, Japan hJohn A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA iSchool of Life Sciences, University of Westminster, London, UK jState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China kMRC-HPA Centre for Environment and Health, Imperial College London, London, UK *David Curb deceased.\r\n","annee":"2013","mois":"6","numero":"31:6","page":"1144-1150","auteurs":[{"ID":15218,"post_author":"0","post_date":"2018-12-03 19:21:36","post_date_gmt":"2018-12-03 18:21:36","post_content":"","post_title":"Jeremiah Stamler","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jeremiah-stamler","to_ping":"","pinged":"","post_modified":"2018-12-03 19:21:36","post_modified_gmt":"2018-12-03 18:21:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jeremiah-stamler\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":1244,"post_author":"0","post_date":"2018-12-03 15:57:38","post_date_gmt":"2018-12-03 14:57:38","post_content":"","post_title":"Ian J Brown","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ian-j-brown","to_ping":"","pinged":"","post_modified":"2018-12-03 15:57:38","post_modified_gmt":"2018-12-03 14:57:38","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ian-j-brown\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":25829,"post_author":"0","post_date":"2018-12-03 22:28:30","post_date_gmt":"2018-12-03 21:28:30","post_content":"","post_title":"Kyoko Miura","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kyoko-miura","to_ping":"","pinged":"","post_modified":"2018-12-03 22:28:30","post_modified_gmt":"2018-12-03 21:28:30","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kyoko-miura\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":34691,"post_author":"0","post_date":"2018-12-04 00:33:29","post_date_gmt":"2018-12-03 23:33:29","post_content":"","post_title":"J HYPERTENS","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-hypertens","to_ping":"","pinged":"","post_modified":"2018-12-04 00:33:29","post_modified_gmt":"2018-12-03 23:33:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/j-hypertens\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n