{"id":32082,"date":"2014-08-01T00:00:00","date_gmt":"2018-12-03T22:54:14","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/bioavailability-of-vitamin-d2-from-enriched-mushrooms-in-prediabetic\/"},"modified":"2018-12-03T23:54:14","modified_gmt":"2018-12-03T22:54:14","slug":"bioavailability-of-vitamin-d2-from-enriched-mushrooms-in-prediabetic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/bioavailability-of-vitamin-d2-from-enriched-mushrooms-in-prediabetic\/","title":{"rendered":"Bioavailability of vitamin D2 from enriched mushrooms in prediabetic adults: a randomized controlled trial."},"content":{"rendered":"<p style=\"text-align: justify\"><strong>BACKGROUND \/ OBJECTIVES:<\/strong><br \/>\nBased on the growing evidence of risk reduction from fresh fruit and vegetable consumption and an inverse relationship between serum 25-hydroxyvitamin D (25OHD) and the risk of type 2 diabetes (T2D), we determined the benefits of regularly consuming vitamin D-enriched mushrooms in a prediabetic cohort. Exposing edible mushrooms to ultraviolet B (UVB) light increases vitamin D2 (D2) and raises serum 25OHD2 in healthy young adults; however, their benefit to deficient prediabetics and glucose metabolism remains untested.<\/p>\n<p style=\"text-align: justify\"><strong>SUBJECTS \/ METHODS:<\/strong><br \/>\nForty-three prediabetic, D-deficient adults (25OHD&le;20&thinsp;ng\/ml), BMI&gt;25 were randomized to four groups consuming daily entr&eacute;es containing 100&thinsp;g fresh sliced cooked mushrooms prepared by a chef for 16 weeks. Two groups were fed UVB-treated mushrooms initially containing: 600&thinsp;IU D2 or 4000&thinsp;IU D2; each one also received one capsule of placebo daily. Two control groups were fed untreated mushrooms and D3 dietary supplements at two label doses: 600&thinsp;IU D3 and 4000&thinsp;IU D3. D2 and D3 content were analyzed in mushrooms, before and after cooking and in over-the-counter supplements.<\/p>\n<p style=\"text-align: justify\"><strong>RESULTS:<\/strong><br \/>\nAfter 16 weeks, both D2-UVB-mushroom entr&eacute;e doses, which were significantly lower after cooking, produced modest or no increases in 25OHD2 or total 25OHD relative to the positive control subjects who actually consumed about 1242 and 7320&thinsp;IU per day of D3 (higher than stated on the label).<\/p>\n<p style=\"text-align: justify\"><strong>CONCLUSIONS:<\/strong><br \/>\nUnanticipated D2 cooking loss from fresh UVB mushrooms and probable low absorption and\/or hydroxylation may explain the smaller increase in 25OHD2 in our prediabetic overweight\/obese cohort compared with past findings in younger, healthy subjects. Moreover, no dose or vitamin D source was associated with modifying T2D risk factors.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-32082","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.\r\npeter.heeger@mssm.edu","annee":"2014","mois":"8","numero":"68:10","page":"1154-60","auteurs":[{"ID":32077,"post_author":"0","post_date":"2018-12-03 23:54:10","post_date_gmt":"2018-12-03 22:54:10","post_content":"","post_title":"Robert B Beelman","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"robert-b-beelman","to_ping":"","pinged":"","post_modified":"2018-12-03 23:54:10","post_modified_gmt":"2018-12-03 22:54:10","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/robert-b-beelman\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32078,"post_author":"0","post_date":"2018-12-03 23:54:11","post_date_gmt":"2018-12-03 22:54:11","post_content":"","post_title":"A Mehrotra","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"a-mehrotra","to_ping":"","pinged":"","post_modified":"2018-12-03 23:54:11","post_modified_gmt":"2018-12-03 22:54:11","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/a-mehrotra\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32079,"post_author":"0","post_date":"2018-12-03 23:54:12","post_date_gmt":"2018-12-03 22:54:12","post_content":"","post_title":"M S Calvo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"m-s-calvo","to_ping":"","pinged":"","post_modified":"2018-12-03 23:54:12","post_modified_gmt":"2018-12-03 22:54:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/m-s-calvo\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":16553,"post_author":"0","post_date":"2018-12-03 19:40:29","post_date_gmt":"2018-12-03 18:40:29","post_content":"","post_title":"Emile Levy","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"emile-levy","to_ping":"","pinged":"","post_modified":"2018-12-03 19:40:29","post_modified_gmt":"2018-12-03 18:40:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/emile-levy\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32080,"post_author":"0","post_date":"2018-12-03 23:54:13","post_date_gmt":"2018-12-03 22:54:13","post_content":"","post_title":"J Siuty","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-siuty","to_ping":"","pinged":"","post_modified":"2018-12-03 23:54:13","post_modified_gmt":"2018-12-03 22:54:13","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/j-siuty\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32081,"post_author":"0","post_date":"2018-12-03 23:54:13","post_date_gmt":"2018-12-03 22:54:13","post_content":"","post_title":"M D Kalaras","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"m-d-kalaras","to_ping":"","pinged":"","post_modified":"2018-12-03 23:54:13","post_modified_gmt":"2018-12-03 22:54:13","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/m-d-kalaras\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":24000,"post_author":"0","post_date":"2018-12-03 21:43:05","post_date_gmt":"2018-12-03 20:43:05","post_content":"","post_title":"Jaime Uribarri","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jaime-uribarri","to_ping":"","pinged":"","post_modified":"2018-12-03 21:43:05","post_modified_gmt":"2018-12-03 20:43:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jaime-uribarri\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1732,"post_author":"0","post_date":"2018-12-03 16:02:02","post_date_gmt":"2018-12-03 15:02:02","post_content":"","post_title":"Eur J Clin Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"eur-j-clin-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 16:02:02","post_modified_gmt":"2018-12-03 15:02:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/eur-j-clin-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ 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