{"id":32006,"date":"2014-08-01T00:00:00","date_gmt":"2018-12-03T22:53:01","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/maternal-protein-intake-during-pregnancy-and-offspring-overweight\/"},"modified":"2018-12-03T23:53:01","modified_gmt":"2018-12-03T22:53:01","slug":"maternal-protein-intake-during-pregnancy-and-offspring-overweight","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/maternal-protein-intake-during-pregnancy-and-offspring-overweight\/","title":{"rendered":"Maternal protein intake during pregnancy and offspring overweight 20 y later."},"content":{"rendered":"<p><strong>BACKGROUND<\/strong><br \/>\nAnimal studies have shown that protein intake in pregnancy may influence offspring fat metabolism and adiposity. The macronutrient ratio in human pregnancy appears to be important for offspring glucose tolerance; however, less is known about the influence on offspring adiposity.<\/p>\n<p><strong>OBJECTIVE<\/strong><br \/>\nWe examined the relation between maternal dietary protein intake during pregnancy and offspring anthropometric measures and biomarkers of adiposity and glucose metabolism.<\/p>\n<p><strong>DESIGN<\/strong><br \/>\nWe used a prospective cohort of 965 Danish pregnant women recruited in 1988-1989 with offspring follow-up at 19-21 y. Macronutrient intake was collected in gestational week 30, and we divided protein according to its source (animal and vegetable including cereals). Offspring body mass index (BMI; in kg\/m(2)) and waist circumference were recorded at follow-up (n = 695-697), and biomarkers were quantified in a subset (n = 443) of participants. We used multivariable linear and log-binomial regression to calculate effect estimates and 95% CIs for a 1:1-g substitution of carbohydrates for protein.<\/p>\n<p><strong>RESULTS<\/strong><br \/>\nOffspring mean (&plusmn;SD) BMI was 22.1 &plusmn; 3.3 and 22.8 &plusmn; 2.9 for women and men, respectively. The prevalence of overweight (BMI ?25) was 16.9% for women and 19.1% for men. We showed that a 1:1-g substitution of animal protein for carbohydrates increased risk of BMI ?25 in female [quartile 4 compared with quartile 1: risk ratio (RR): 3.36; 95% CI: 1.52, 7.42] and male (quartile 4 compared with quartile 1: RR: 2.22; 95% CI: 0.92, 5.35) offspring. These results appeared to be accounted for by protein from meat sources. The results could not be explained by postnatal risk factors.<\/p>\n<p><strong>CONCLUSIONS<\/strong><br \/>\nProtein from animal sources, primarily meat products, consumed during pregnancy may increase risk of overweight in offspring; this association appeared to be stronger for female offspring. Because of the lack of information on postnatal exposure in this cohort, these results are hypothesis-generating and need to be replicating in other cohorts.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-32006","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"From the Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark (EM, SFO, and TIH); the Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark (DR and BHB); the Department of Pediatrics, Aarhus University Hospital, Skejby, Denmark (TBH); the Faculty of Science, University of Copenhagen, Frederiksberg, Denmark (MAR); the Department of Nutrition, Harvard School of Public Health, Boston, MA (SFO); the Faculty of Food Science and Nutrition, School of Health Sciences, University of Iceland, Reykjavik, Iceland (TIH); and the Unit for Nutrition Research, Landspitali University Hospital, Reykjavik, Iceland (TIH).\r\nkmv@ssi.dk","annee":"2014","mois":"8","numero":"100:4","page":"1139-48","auteurs":[{"ID":31999,"post_author":"0","post_date":"2018-12-03 23:52:57","post_date_gmt":"2018-12-03 22:52:57","post_content":"","post_title":"Thorhallur Ingi Halldorsson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"thorhallur-ingi-halldorsson","to_ping":"","pinged":"","post_modified":"2018-12-03 23:52:57","post_modified_gmt":"2018-12-03 22:52:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/thorhallur-ingi-halldorsson\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32000,"post_author":"0","post_date":"2018-12-03 23:52:57","post_date_gmt":"2018-12-03 22:52:57","post_content":"","post_title":"Sjurdur F Olsen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sjurdur-f-olsen","to_ping":"","pinged":"","post_modified":"2018-12-03 23:52:57","post_modified_gmt":"2018-12-03 22:52:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sjurdur-f-olsen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32001,"post_author":"0","post_date":"2018-12-03 23:52:58","post_date_gmt":"2018-12-03 22:52:58","post_content":"","post_title":"Ekaterina Maslova","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ekaterina-maslova","to_ping":"","pinged":"","post_modified":"2018-12-03 23:52:58","post_modified_gmt":"2018-12-03 22:52:58","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ekaterina-maslova\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32002,"post_author":"0","post_date":"2018-12-03 23:52:59","post_date_gmt":"2018-12-03 22:52:59","post_content":"","post_title":"Dorte Rytter","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dorte-rytter","to_ping":"","pinged":"","post_modified":"2018-12-03 23:52:59","post_modified_gmt":"2018-12-03 22:52:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dorte-rytter\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32003,"post_author":"0","post_date":"2018-12-03 23:52:59","post_date_gmt":"2018-12-03 22:52:59","post_content":"","post_title":"Bodil H Bech","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bodil-h-bech","to_ping":"","pinged":"","post_modified":"2018-12-03 23:52:59","post_modified_gmt":"2018-12-03 22:52:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bodil-h-bech\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32004,"post_author":"0","post_date":"2018-12-03 23:53:00","post_date_gmt":"2018-12-03 22:53:00","post_content":"","post_title":"Tine B Henriksen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"tine-b-henriksen","to_ping":"","pinged":"","post_modified":"2018-12-03 23:53:00","post_modified_gmt":"2018-12-03 22:53:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/tine-b-henriksen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32005,"post_author":"0","post_date":"2018-12-03 23:53:00","post_date_gmt":"2018-12-03 22:53:00","post_content":"","post_title":"Morten A Rasmussen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"morten-a-rasmussen","to_ping":"","pinged":"","post_modified":"2018-12-03 23:53:00","post_modified_gmt":"2018-12-03 22:53:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/morten-a-rasmussen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1720,"post_author":"0","post_date":"2018-12-03 16:01:56","post_date_gmt":"2018-12-03 15:01:56","post_content":"","post_title":"Am J Clin Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-clin-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:56","post_modified_gmt":"2018-12-03 15:01:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-clin-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Maternal protein intake during pregnancy and offspring overweight 20 y later. - Aprifel<\/title>\n<meta name=\"description\" content=\"Maternal protein intake during pregnancy and offspring overweight 20 y later. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" 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