{"id":30631,"date":"2014-11-01T00:00:00","date_gmt":"2018-12-03T22:34:24","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/a-novel-combined-biomarker-including-plasma-carotenoids\/"},"modified":"2018-12-03T23:34:24","modified_gmt":"2018-12-03T22:34:24","slug":"a-novel-combined-biomarker-including-plasma-carotenoids","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/a-novel-combined-biomarker-including-plasma-carotenoids\/","title":{"rendered":"A Novel Combined Biomarker including Plasma Carotenoids, Vitamin C, and Ferric Reducing Antioxidant Power Is More Strongly Associated with Fruit and Vegetable Intake than the Individual Components."},"content":{"rendered":"<p style=\"text-align: justify\"><strong>BACKGROUND<\/strong><br \/>\nMonitoring of fruit and vegetable (F&amp;V) intake is fraught with difficulties. Available dietary assessment methods are associated with considerable error, and the use of biomarkers offers an attractive alternative. Few studies to date have examined the use of plasma biomarkers to monitor or predict the F&amp;V intake of volunteers consuming a wide range of intakes from both habitual F&amp;V and manipulated diets.<\/p>\n<p style=\"text-align: justify\"><strong>OBJECTIVE<\/strong><br \/>\nThis study tested the hypothesis that an integrated biomarker calculated from a combination of plasma vitamin C, cholesterol-adjusted carotenoid concentration and Ferric Reducing Antioxidant Power (FRAP) had more power to predict F&amp;V intake than each individual biomarker.<\/p>\n<p style=\"text-align: justify\"><strong>METHODS<\/strong><br \/>\nData from a randomized controlled dietary intervention study [FLAVURS (Flavonoids University of Reading Study); n = 154] in which the test groups observed sequential increases of 2.3, 3.2, and 4.2 portions of F&amp;Vs every 6 wk across an 18-wk period were used in this study.<\/p>\n<p style=\"text-align: justify\"><strong>RESULTS<\/strong><br \/>\nAn integrated plasma biomarker was devised that included plasma vitamin C, total cholesterol-adjusted carotenoids, and FRAP values, which better correlated with F&amp;V intake (r = 0.47, P &lt; 0.001) than the individual biomarkers (r = 0.33, P &lt; 0.01; r = 0.37, P &lt; 0.001; and r = 0.14, respectively; P = 0.099). Inclusion of urinary potassium concentration did not significantly improve the correlation. The integrated plasma biomarker predicted F&amp;V intake more accurately than did plasma total cholesterol-adjusted carotenoid concentration, with the difference being significant at visit 2 (P &lt; 0.001) and with a tendency to be significant at visit 1 (P = 0.07).<\/p>\n<p style=\"text-align: justify\"><strong>CONCLUSION<\/strong><br \/>\nEither plasma total cholesterol-adjusted carotenoid concentration or the integrated biomarker could be used to distinguish between high- and moderate-F&amp;V consumers.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-30631","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Hugh Sinclair Unit of Human Nutrition and Institute of Cardiovascular and Metabolic Research, Department of Food and Nutritional Sciences, The University of Reading, Reading, Berks, UK \r\nm.h.gordon@reading.ac.uk","annee":"2014","mois":"11","numero":"144:11","page":"1866-72","auteurs":[{"ID":30625,"post_author":"0","post_date":"2018-12-03 23:34:20","post_date_gmt":"2018-12-03 22:34:20","post_content":"","post_title":"Trevor W George","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"trevor-w-george","to_ping":"","pinged":"","post_modified":"2018-12-03 23:34:20","post_modified_gmt":"2018-12-03 22:34:20","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/trevor-w-george\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":30626,"post_author":"0","post_date":"2018-12-03 23:34:21","post_date_gmt":"2018-12-03 22:34:21","post_content":"","post_title":"Yannan Jin","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"yannan-jin","to_ping":"","pinged":"","post_modified":"2018-12-03 23:34:21","post_modified_gmt":"2018-12-03 22:34:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/yannan-jin\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":4799,"post_author":"0","post_date":"2018-12-03 17:21:05","post_date_gmt":"2018-12-03 16:21:05","post_content":"","post_title":"Orla B Kennedy","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"orla-b-kennedy","to_ping":"","pinged":"","post_modified":"2018-12-03 17:21:05","post_modified_gmt":"2018-12-03 16:21:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/orla-b-kennedy\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":30627,"post_author":"0","post_date":"2018-12-03 23:34:21","post_date_gmt":"2018-12-03 22:34:21","post_content":"","post_title":"Anne-marie Minihane","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"anne-marie-minihane","to_ping":"","pinged":"","post_modified":"2018-12-03 23:34:21","post_modified_gmt":"2018-12-03 22:34:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/anne-marie-minihane\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":30628,"post_author":"0","post_date":"2018-12-03 23:34:22","post_date_gmt":"2018-12-03 22:34:22","post_content":"","post_title":"Michael H Gordon","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"michael-h-gordon","to_ping":"","pinged":"","post_modified":"2018-12-03 23:34:22","post_modified_gmt":"2018-12-03 22:34:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/michael-h-gordon\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":5596,"post_author":"0","post_date":"2018-12-03 17:29:33","post_date_gmt":"2018-12-03 16:29:33","post_content":"","post_title":"Julie A Lovegrove","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"julie-a-lovegrove","to_ping":"","pinged":"","post_modified":"2018-12-03 17:29:33","post_modified_gmt":"2018-12-03 16:29:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/julie-a-lovegrove\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":30629,"post_author":"0","post_date":"2018-12-03 23:34:23","post_date_gmt":"2018-12-03 22:34:23","post_content":"","post_title":"Dauren Alimbetov","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dauren-alimbetov","to_ping":"","pinged":"","post_modified":"2018-12-03 23:34:23","post_modified_gmt":"2018-12-03 22:34:23","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dauren-alimbetov\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":30630,"post_author":"0","post_date":"2018-12-03 23:34:23","post_date_gmt":"2018-12-03 22:34:23","post_content":"","post_title":"Mary F-F Chong","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mary-f-f-chong-2","to_ping":"","pinged":"","post_modified":"2018-12-03 23:34:23","post_modified_gmt":"2018-12-03 22:34:23","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mary-f-f-chong-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":24269,"post_author":"0","post_date":"2018-12-03 21:50:00","post_date_gmt":"2018-12-03 20:50:00","post_content":"","post_title":"Jeremy P E Spencer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jeremy-p-e-spencer","to_ping":"","pinged":"","post_modified":"2018-12-03 21:50:00","post_modified_gmt":"2018-12-03 20:50:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jeremy-p-e-spencer\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":22509,"post_author":"0","post_date":"2018-12-03 21:06:01","post_date_gmt":"2018-12-03 20:06:01","post_content":"","post_title":"Kieran M Tuohy","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kieran-m-tuohy","to_ping":"","pinged":"","post_modified":"2018-12-03 21:06:01","post_modified_gmt":"2018-12-03 20:06:01","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kieran-m-tuohy\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":29917,"post_author":"0","post_date":"2018-12-03 23:25:24","post_date_gmt":"2018-12-03 22:25:24","post_content":"","post_title":"J Nutr.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-nutr","to_ping":"","pinged":"","post_modified":"2018-12-03 23:25:24","post_modified_gmt":"2018-12-03 22:25:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/j-nutr\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A Novel Combined Biomarker including Plasma Carotenoids, Vitamin C, and Ferric Reducing Antioxidant Power Is More Strongly Associated with Fruit and Vegetable Intake than the Individual Components. - Aprifel<\/title>\n<meta name=\"description\" content=\"A Novel Combined Biomarker including Plasma Carotenoids, Vitamin C, and Ferric Reducing Antioxidant Power Is More Strongly Associated 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