{"id":30233,"date":"2014-11-01T00:00:00","date_gmt":"2018-12-03T22:29:28","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-vitamin-e-from-supplements-and-diet-on-colonic-i\/"},"modified":"2018-12-03T23:29:28","modified_gmt":"2018-12-03T22:29:28","slug":"effects-of-vitamin-e-from-supplements-and-diet-on-colonic-i","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-vitamin-e-from-supplements-and-diet-on-colonic-i\/","title":{"rendered":"Effects of Vitamin E From Supplements and Diet on Colonic &#945;- and &#947;-tocopherol Concentrations in Persons at Increased Colon Cancer Risk."},"content":{"rendered":"<p>The available evidence indicates that &gamma;-tocopherol has more potential for colon cancer prevention than &alpha;-tocopherol, but little is known about the effects of foods and supplements on tocopherol levels in human colon. This study randomized 120 subjects at increased colon cancer risk to either a Mediterranean or a Healthy Eating diet for 6 mo. Supplement use was reported by 39% of the subjects, and vitamin E intake from supplements was twofold higher than that from foods. Serum &alpha;-tocopherol at baseline was positively predicted by dietary intakes of synthetic vitamin E in foods and supplements but not by natural &alpha;-tocopherol from foods. For serum &gamma;-tocopherol, dietary &gamma;-tocopherol was not a predictor, but dietary &alpha;-tocopherol was a negative predictor. Unlike with serum, the data supported a role for metabolic factors, and not a direct effect of diet, in governing concentrations of both &alpha;- and &gamma;-tocopherol in colon. The Mediterranean intervention increased intakes of natural &alpha;-tocopherol, which is high in nuts, and decreased intakes of &gamma;-tocopherol, which is low in olive oil. These dietary changes had no significant effects on colon tocopherols. The impact of diet on colon tocopherols therefore appears to be limited.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-30233","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Family Medicine , University of Michigan , Ann Arbor , Michigan , USA.\r\nzoralong@umich.edu","annee":"2014","mois":"11","numero":":","page":"1-9","auteurs":[{"ID":26008,"post_author":"0","post_date":"2018-12-03 22:31:26","post_date_gmt":"2018-12-03 21:31:26","post_content":"","post_title":"Jan Barendregt","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jan-barendregt","to_ping":"","pinged":"","post_modified":"2018-12-03 22:31:26","post_modified_gmt":"2018-12-03 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Turgeon","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"d-kim-turgeon","to_ping":"","pinged":"","post_modified":"2018-12-03 22:53:27","post_modified_gmt":"2018-12-03 21:53:27","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/d-kim-turgeon\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":30232,"post_author":"0","post_date":"2018-12-03 23:29:28","post_date_gmt":"2018-12-03 22:29:28","post_content":"","post_title":"Nutr Cancer.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nutr-cancer-2","to_ping":"","pinged":"","post_modified":"2018-12-03 23:29:28","post_modified_gmt":"2018-12-03 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