{"id":28292,"date":"2015-03-01T00:00:00","date_gmt":"2018-12-03T22:04:57","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/antioxidant-and-anti-atherogenic-properties-of-phenolic\/"},"modified":"2018-12-03T23:04:57","modified_gmt":"2018-12-03T22:04:57","slug":"antioxidant-and-anti-atherogenic-properties-of-phenolic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/antioxidant-and-anti-atherogenic-properties-of-phenolic\/","title":{"rendered":"Antioxidant and anti-atherogenic properties of phenolic acid and flavonol fractions of fruits of &lsquo;Amari&rsquo; and &lsquo;Hallawi&rsquo; date (Phoenix dactylifera L.) varieties."},"content":{"rendered":"<p style=\"text-align: justify\">Date (Phoenix dactylifera L.) fruit phenolic-acid or flavonol fractions were examined in vitro for antioxidant and anti-atherogenic properties. Two fractions of each subgroup were prepared from two date varieties, &#039;Amari&#039; and &#039;Hallawi&#039;, by solid phase extraction on C18. The fractions were analyzed for phenolics&#039; composition by RP-HPLC, and tested for ferric-reducing antioxidant power, free radical scavenging capacity, inhibition of Cu(2+)-induced LDL-oxidation and enhancement of HDL-mediated cholesterol efflux from macrophages. All four fractions exhibited variable capacities to reduce ferric ions, scavenge radicals and inhibit LDL-oxidation. Flavonol fractions were considerably better inhibitors of LDL-oxidation compared to phenolic-acid fractions, with IC50 of 9-31 nmol GAE mL(-1) compared to 85-116 nmol GAE mL(-1), respectively. Only the flavonol fractions stimulated cholesterol removal from macrophages. Within each subgroup, the levels of all the activities varied with fraction composition. The results demonstrated strong structure-activity relationships for date phenolics, and identified date flavonols as potential anti-atherogenic bioactives.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-28292","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Southern Arava Research and Development, M. P. Hevel Eilot 88820, Israel.\r\nThe Lipid Research Laboratory, Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences, Technion-Israel Institute of Technology, Rambam Medical Center, Haifa 31096, Israel.","annee":"2015","mois":"3","numero":"63:12","page":"3189-95","auteurs":[{"ID":28286,"post_author":"0","post_date":"2018-12-03 23:04:53","post_date_gmt":"2018-12-03 22:04:53","post_content":"","post_title":"Hamutal Borochov-Neori","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hamutal-borochov-neori","to_ping":"","pinged":"","post_modified":"2018-12-03 23:04:53","post_modified_gmt":"2018-12-03 22:04:53","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hamutal-borochov-neori\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":28287,"post_author":"0","post_date":"2018-12-03 23:04:54","post_date_gmt":"2018-12-03 22:04:54","post_content":"","post_title":"Sylvie Judeinstein","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sylvie-judeinstein","to_ping":"","pinged":"","post_modified":"2018-12-03 23:04:54","post_modified_gmt":"2018-12-03 22:04:54","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sylvie-judeinstein\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":28288,"post_author":"0","post_date":"2018-12-03 23:04:55","post_date_gmt":"2018-12-03 22:04:55","post_content":"","post_title":"Amnon Greenberg","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"amnon-greenberg","to_ping":"","pinged":"","post_modified":"2018-12-03 23:04:55","post_modified_gmt":"2018-12-03 22:04:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/amnon-greenberg\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":28289,"post_author":"0","post_date":"2018-12-03 23:04:55","post_date_gmt":"2018-12-03 22:04:55","post_content":"","post_title":"Nina Volkova","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nina-volkova","to_ping":"","pinged":"","post_modified":"2018-12-03 23:04:55","post_modified_gmt":"2018-12-03 22:04:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/nina-volkova\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":28290,"post_author":"0","post_date":"2018-12-03 23:04:56","post_date_gmt":"2018-12-03 22:04:56","post_content":"","post_title":"Mira Rosenblat","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mira-rosenblat","to_ping":"","pinged":"","post_modified":"2018-12-03 23:04:56","post_modified_gmt":"2018-12-03 22:04:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mira-rosenblat\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":28291,"post_author":"0","post_date":"2018-12-03 23:04:57","post_date_gmt":"2018-12-03 22:04:57","post_content":"","post_title":"Michael Aviram","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"michael-aviram","to_ping":"","pinged":"","post_modified":"2018-12-03 23:04:57","post_modified_gmt":"2018-12-03 22:04:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/michael-aviram\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1648,"post_author":"0","post_date":"2018-12-03 16:01:16","post_date_gmt":"2018-12-03 15:01:16","post_content":"","post_title":"Journal of agricultural and food chemistry","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"journal-of-agricultural-and-food-chemistry","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:16","post_modified_gmt":"2018-12-03 15:01:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/journal-of-agricultural-and-food-chemistry\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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