{"id":27919,"date":"2015-03-01T00:00:00","date_gmt":"2018-12-03T21:59:41","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/a-novel-testing-model-for-opportunistic-screening-of-pre-diabetes\/"},"modified":"2018-12-03T22:59:41","modified_gmt":"2018-12-03T21:59:41","slug":"a-novel-testing-model-for-opportunistic-screening-of-pre-diabetes","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/a-novel-testing-model-for-opportunistic-screening-of-pre-diabetes\/","title":{"rendered":"A Novel Testing Model for Opportunistic Screening of Pre-Diabetes and Diabetes among U.S. Adults."},"content":{"rendered":"<p style=\"text-align: justify\"><strong>OBJECTIVE<\/strong><br \/>\nThe study aim was to evaluate the performance of a novel simultaneous testing model, based on the Finnish Diabetes Risk Score (FINDRISC) and HbA1c, in detecting undiagnosed diabetes and pre-diabetes in Americans.<\/p>\n<p style=\"text-align: justify\"><strong>RESEARCH DESIGN AND METHODS<\/strong><br \/>\nThis cross-sectional analysis included 3,886 men and women (&ge; 20 years) without known diabetes from the U.S. National Health and Nutrition Examination Survey (NHANES) 2005-2010. The FINDRISC was developed based on eight variables (age, BMI, waist circumference, use of antihypertensive drug, history of high blood glucose, family history of diabetes, daily physical activity and fruit &amp; vegetable intake). The sensitivity, specificity, and the receiver operating characteristic (ROC) curve of the testing model were calculated for undiagnosed diabetes and pre-diabetes, determined by oral glucose tolerance test (OGTT).<\/p>\n<p style=\"text-align: justify\"><strong>RESULTS<\/strong><br \/>\nThe prevalence of undiagnosed diabetes was 7.0% and 43.1% for pre-diabetes (27.7% for isolated impaired fasting glucose (IFG), 5.1% for impaired glucose tolerance (IGT), and 10.3% for having both IFG and IGT). The sensitivity and specificity of using the HbA1c alone was 24.2% and 99.6% for diabetes (cutoff of &ge;6.5%), and 35.2% and 86.4% for pre-diabetes (cutoff of &ge;5.7%). The sensitivity and specificity of using the FINDRISC alone (cutoff of &ge;9) was 79.1% and 48.6% for diabetes and 60.2% and 61.4% for pre-diabetes. Using the simultaneous testing model with a combination of FINDRISC and HbA1c improved the sensitivity to 84.2% for diabetes and 74.2% for pre-diabetes. The specificity for the simultaneous testing model was 48.4% of diabetes and 53.0% for pre-diabetes.<\/p>\n<p style=\"text-align: justify\"><strong>CONCLUSIONS<\/strong><br \/>\nThis simultaneous testing model is a practical and valid tool in diabetes screening in the general U.S. population.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-27919","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"The First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi, China.","annee":"2015","mois":"3","numero":"10:3","page":"e0120382","auteurs":[{"ID":27917,"post_author":"0","post_date":"2018-12-03 22:59:39","post_date_gmt":"2018-12-03 21:59:39","post_content":"","post_title":"Yurong Zhang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"yurong-zhang","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:39","post_modified_gmt":"2018-12-03 21:59:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/yurong-zhang\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6118,"post_author":"0","post_date":"2018-12-03 17:35:00","post_date_gmt":"2018-12-03 16:35:00","post_content":"","post_title":"Gang Hu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"gang-hu","to_ping":"","pinged":"","post_modified":"2018-12-03 17:35:00","post_modified_gmt":"2018-12-03 16:35:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/gang-hu\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":24123,"post_author":"0","post_date":"2018-12-03 21:46:32","post_date_gmt":"2018-12-03 20:46:32","post_content":"","post_title":"Lun Zhang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lun-zhang","to_ping":"","pinged":"","post_modified":"2018-12-03 21:46:32","post_modified_gmt":"2018-12-03 20:46:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/lun-zhang\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27918,"post_author":"0","post_date":"2018-12-03 22:59:40","post_date_gmt":"2018-12-03 21:59:40","post_content":"","post_title":"Rachel Mayo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rachel-mayo","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:40","post_modified_gmt":"2018-12-03 21:59:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/rachel-mayo\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":11158,"post_author":"0","post_date":"2018-12-03 18:31:53","post_date_gmt":"2018-12-03 17:31:53","post_content":"","post_title":"Liwei Chen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"liwei-chen","to_ping":"","pinged":"","post_modified":"2018-12-03 18:31:53","post_modified_gmt":"2018-12-03 17:31:53","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/liwei-chen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1142,"post_author":"0","post_date":"2018-12-03 15:56:43","post_date_gmt":"2018-12-03 14:56:43","post_content":"","post_title":"PloS one","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"plos-one","to_ping":"","pinged":"","post_modified":"2018-12-03 15:56:43","post_modified_gmt":"2018-12-03 14:56:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/plos-one\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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