{"id":27911,"date":"2015-04-01T00:00:00","date_gmt":"2018-12-03T21:59:35","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/metabolic-and-physiologic-effects-from-consuming-a-hunter-gatherer\/"},"modified":"2018-12-03T22:59:35","modified_gmt":"2018-12-03T21:59:35","slug":"metabolic-and-physiologic-effects-from-consuming-a-hunter-gatherer","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/metabolic-and-physiologic-effects-from-consuming-a-hunter-gatherer\/","title":{"rendered":"Metabolic and physiologic effects from consuming a hunter-gatherer (Paleolithic)-type diet in type 2 diabetes."},"content":{"rendered":"<p style=\"text-align: justify\"><strong>BACKGROUND\/OBJECTIVES<\/strong><br \/>\nThe contemporary American diet figures centrally in the pathogenesis of numerous chronic diseases- &#039;diseases of civilization&#039;-such as obesity and diabetes. We investigated in type 2 diabetes whether a diet similar to that consumed by our pre-agricultural hunter-gatherer ancestors (&#039;Paleolithic&#039; type diet) confers health benefits.<\/p>\n<p style=\"text-align: justify\"><strong>SUBJECTS\/METHODS<\/strong><br \/>\nWe performed an outpatient, metabolically controlled diet study in type 2 diabetes patients. We compared the findings in 14 participants consuming a Paleo diet comprising lean meat, fruits, vegetables and nuts, and excluding added salt, and non-Paleolithic-type foods comprising cereal grains, dairy or legumes, with 10 participants on a diet based on recommendations by the American Diabetes Association (ADA) containing moderate salt intake, low-fat dairy, whole grains and legumes. There were three ramp-up diets for 7 days, then 14 days of the test diet. Outcomes included the following: mean arterial blood pressure; 24-h urine electrolytes; hemoglobin A1c and fructosamine levels; insulin resistance by euglycemic hyperinsulinemic clamp and lipid levels.<\/p>\n<p style=\"text-align: justify\"><strong>RESULTS<\/strong><br \/>\nBoth groups had improvements in metabolic measures, but the Paleo diet group had greater benefits on glucose control and lipid profiles. Also, on the Paleo diet, the most insulin-resistant subjects had a significant improvement in insulin sensitivity (r=0.40, P=0.02), but no such effect was seen in the most insulin-resistant subjects on the ADA diet (r= 0.39, P=0.3).<\/p>\n<p style=\"text-align: justify\"><strong>CONCLUSIONS<\/strong><br \/>\nEven short-term consumption of a Paleolithic-type diet improved glucose control and lipid profiles in people with type 2 diabetes compared with a conventional diet containing moderate salt intake, low-fat dairy, whole grains and legumes.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-27911","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Medicine, University of California San Francisco, San Francisco, CA, USA.","annee":"2015","mois":"4","numero":"","page":"","auteurs":[{"ID":27903,"post_author":"0","post_date":"2018-12-03 22:59:29","post_date_gmt":"2018-12-03 21:59:29","post_content":"","post_title":"M Schloetter","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"m-schloetter","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:29","post_modified_gmt":"2018-12-03 21:59:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/m-schloetter\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27904,"post_author":"0","post_date":"2018-12-03 22:59:30","post_date_gmt":"2018-12-03 21:59:30","post_content":"","post_title":"A Sebastian","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"a-sebastian","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:30","post_modified_gmt":"2018-12-03 21:59:30","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/a-sebastian\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27905,"post_author":"0","post_date":"2018-12-03 22:59:31","post_date_gmt":"2018-12-03 21:59:31","post_content":"","post_title":"U Masharani","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"u-masharani","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:31","post_modified_gmt":"2018-12-03 21:59:31","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/u-masharani\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27906,"post_author":"0","post_date":"2018-12-03 22:59:31","post_date_gmt":"2018-12-03 21:59:31","post_content":"","post_title":"P Sherchan","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"p-sherchan","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:31","post_modified_gmt":"2018-12-03 21:59:31","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/p-sherchan\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27907,"post_author":"0","post_date":"2018-12-03 22:59:32","post_date_gmt":"2018-12-03 21:59:32","post_content":"","post_title":"S Stratford","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"s-stratford","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:32","post_modified_gmt":"2018-12-03 21:59:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/s-stratford\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27908,"post_author":"0","post_date":"2018-12-03 22:59:33","post_date_gmt":"2018-12-03 21:59:33","post_content":"","post_title":"A Xiao","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"a-xiao","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:33","post_modified_gmt":"2018-12-03 21:59:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/a-xiao\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27909,"post_author":"0","post_date":"2018-12-03 22:59:33","post_date_gmt":"2018-12-03 21:59:33","post_content":"","post_title":"M Nolte Kennedy","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"m-nolte-kennedy","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:33","post_modified_gmt":"2018-12-03 21:59:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/m-nolte-kennedy\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27910,"post_author":"0","post_date":"2018-12-03 22:59:34","post_date_gmt":"2018-12-03 21:59:34","post_content":"","post_title":"L Frassetto","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"l-frassetto","to_ping":"","pinged":"","post_modified":"2018-12-03 22:59:34","post_modified_gmt":"2018-12-03 21:59:34","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/l-frassetto\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1262,"post_author":"0","post_date":"2018-12-03 15:57:47","post_date_gmt":"2018-12-03 14:57:47","post_content":"","post_title":"European journal of clinical nutrition","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"european-journal-of-clinical-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-03 15:57:47","post_modified_gmt":"2018-12-03 14:57:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/european-journal-of-clinical-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 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