{"id":21657,"date":"2016-02-01T00:00:00","date_gmt":"2018-12-03T19:52:43","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/association-of-adherence-to-a-mediterranean-diet-with-glycemic\/"},"modified":"2018-12-03T20:52:43","modified_gmt":"2018-12-03T19:52:43","slug":"association-of-adherence-to-a-mediterranean-diet-with-glycemic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/association-of-adherence-to-a-mediterranean-diet-with-glycemic\/","title":{"rendered":"Association of adherence to a Mediterranean diet with glycemic control and cardiovascular risk factors in youth with type I diabetes: the SEARCH Nutrition Ancillary Study."},"content":{"rendered":"

BACKGROUND\/OBJECTIVES<\/strong>
\nThis study aimed to determine the association between a Mediterranean diet and glycemic control and other cardiovascular risk factors among youth with type I diabetes (TID).<\/p>\n

SUBJECTS\/METHODS<\/strong>
\nIncident TID cases aged <20 years at diagnosis between 2002 and 2005 were included. Participants were seen at baseline (N=793), 1-year (N=512) and 5-year follow-up visits (N=501). Mediterranean diet score was assessed using a modified KIDMED index (mKIDMED). Multivariate linear regression and longitudinal mixed model were applied to determine the association between mKIDMED score and log-HbA1c, lipids, blood pressure (BP) and obesity.<\/p>\n

RESULTS<\/strong>
\nIn cross-sectional analyses using baseline data, for individuals with the hemoglobin A1c (HbA1c) of 7.5%, a two-point higher mKIDMED score (1 s.d.) was associated with 0.15% lower HbA1c (P=0.02). A two-point higher mKIDMED score was associated with 4.0 mg\/dl lower total cholesterol (TC) (P=0.006), 3.4 mg\/dl lower low-density lipoprotein cholesterol (LDL-C) (P=0.004), 3.9 mg\/dl lower non-high-density lipoprotein cholesterol (non-HDL-C) (P=0.004) and 0.07 lower LDL-C\/HDL-C ratio (P=0.02). Using longitudinal data, a two-point increase in mKIDMED score was associated with 0.01% lower log-HbA1c (P=0.07), 1.8 mg\/dl lower TC (P=0.05), 1.6 mg\/dl lower LDL-C (P=0.03) and 1.8 mg\/dl lower non-HDL-C (P=0.03) than would otherwise have been expected. HbA1c mediated ∼20% of the association for lipids in both cross-sectional and longitudinal models. An unexpected positive association between mKIDMED score and systolic BP was found among non-Hispanic white youth in cross-sectional analyses (P=0.009). Mediterranean diet was not associated with obesity.<\/p>\n

CONCLUSIONS<\/strong>
\nMediterranean diet may improve glycemic control and cardiovascular health in TID youth.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-21657","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Nutrition, University of North Carolina, Chapel Hill, NC, USA.","annee":"2016","mois":"2","numero":"","page":"","auteurs":[{"ID":21648,"post_author":"0","post_date":"2018-12-03 20:52:38","post_date_gmt":"2018-12-03 19:52:38","post_content":"","post_title":"Mayer-davis","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mayer-davis","to_ping":"","pinged":"","post_modified":"2018-12-03 20:52:38","post_modified_gmt":"2018-12-03 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Lamichhane","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"a-p-lamichhane","to_ping":"","pinged":"","post_modified":"2018-12-03 20:52:39","post_modified_gmt":"2018-12-03 19:52:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/a-p-lamichhane\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":21651,"post_author":"0","post_date":"2018-12-03 20:52:40","post_date_gmt":"2018-12-03 19:52:40","post_content":"","post_title":"J L Crandell","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-l-crandell","to_ping":"","pinged":"","post_modified":"2018-12-03 20:52:40","post_modified_gmt":"2018-12-03 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Lawrence","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-m-lawrence","to_ping":"","pinged":"","post_modified":"2018-12-03 20:52:41","post_modified_gmt":"2018-12-03 19:52:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/j-m-lawrence\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":21655,"post_author":"0","post_date":"2018-12-03 20:52:42","post_date_gmt":"2018-12-03 19:52:42","post_content":"","post_title":"S M Marcovina","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"s-m-marcovina","to_ping":"","pinged":"","post_modified":"2018-12-03 20:52:42","post_modified_gmt":"2018-12-03 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