{"id":21257,"date":"2016-05-01T00:00:00","date_gmt":"2018-12-03T19:47:18","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-combined-healthy-lifestyle-factors-on-functional\/"},"modified":"2018-12-03T20:47:18","modified_gmt":"2018-12-03T19:47:18","slug":"effects-of-combined-healthy-lifestyle-factors-on-functional","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-combined-healthy-lifestyle-factors-on-functional\/","title":{"rendered":"Effects of combined healthy lifestyle factors on functional vascular aging: the Rotterdam Study."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>OBJECTIVE<\/strong><br \/>\nTo evaluate whether components of a healthy lifestyle, combined and individually, are associated with arterial stiffness as a marker of functional vascular aging.<\/p>\n<p style=\"text-align:justify\"><strong>METHODS<\/strong><br \/>\nWe included 3235 participants aged 61-96 years from the Rotterdam Study. Measures of arterial stiffness included: aortic pulse wave velocity and carotid distensibility coefficient. Participants were scored one point for each of healthy lifestyle factors: consumption of five or more of fruits and\/or vegetables per day, 75\u200amin or more vigorous physical activity per week, 18.5\u200a&le;\u200aBMI\u200a&le;\u200a24. 9, never smoked and light-to-moderate alcohol intake (maximum seven glasses for women and 14 glasses for men) per week. Also a combined score (0-5) was computed by adding the five factors. Linear regression analysis was used to evaluate the association of healthy lifestyle and measures of arterial stiffness adjusting for confounders.<\/p>\n<p style=\"text-align:justify\"><strong>RESULTS<\/strong><br \/>\nParticipants had -0.113 [95% confidence interval (CI): -0.196, -0.029] difference in mean aortic pulse wave velocity m\/s per unit increment of the lifestyle factors score, independent of cardiovascular risk factors. Higher fruit and vegetable consumption -0.221 (95% CI: -0.409, -0.034) and physical activity -0.239 (95% CI: -0.433, -0.044) were also significantly associated with reduced aortic pulse wave velocity. The corresponding estimates in carotid distensibility coefficient lacked statistical significance when we adjusted for cardiovascular risk factors.<\/p>\n<p style=\"text-align:justify\"><strong>CONCLUSION<\/strong><br \/>\nCombining multiple healthy lifestyle factors is associated with reduced aortic stiffness, a measure of functional vascular aging and independent of cardiovascular risk factors.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-21257","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Epidemiology bDepartment of Internal Medicine, Section of Geriatric Medicine cDepartment of Biostatistics, Erasmus MC, Rotterdam, the Netherlands.","annee":"2016","mois":"5","numero":"34:5","page":"853-9","auteurs":[{"ID":15976,"post_author":"0","post_date":"2018-12-03 19:33:13","post_date_gmt":"2018-12-03 18:33:13","post_content":"","post_title":"Albert Hofman","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"albert-hofman","to_ping":"","pinged":"","post_modified":"2018-12-03 19:33:13","post_modified_gmt":"2018-12-03 18:33:13","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/albert-hofman\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":2179,"post_author":"0","post_date":"2018-12-03 16:53:08","post_date_gmt":"2018-12-03 15:53:08","post_content":"","post_title":"Oscar H Franco","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"oscar-h-franco","to_ping":"","pinged":"","post_modified":"2018-12-03 16:53:08","post_modified_gmt":"2018-12-03 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Mattace-Raso","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"francesco-u-s-mattace-raso","to_ping":"","pinged":"","post_modified":"2018-12-03 20:47:16","post_modified_gmt":"2018-12-03 19:47:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/francesco-u-s-mattace-raso\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":21256,"post_author":"0","post_date":"2018-12-03 20:47:17","post_date_gmt":"2018-12-03 19:47:17","post_content":"","post_title":"Joost van Rosmalen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"joost-van-rosmalen","to_ping":"","pinged":"","post_modified":"2018-12-03 20:47:17","post_modified_gmt":"2018-12-03 19:47:17","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/joost-van-rosmalen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":12248,"post_author":"0","post_date":"2018-12-03 18:44:24","post_date_gmt":"2018-12-03 17:44:24","post_content":"","post_title":"Frank J A van Rooij","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"frank-j-a-van-rooij","to_ping":"","pinged":"","post_modified":"2018-12-03 18:44:24","post_modified_gmt":"2018-12-03 17:44:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/frank-j-a-van-rooij\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":11901,"post_author":"0","post_date":"2018-12-03 18:40:34","post_date_gmt":"2018-12-03 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