{"id":20314,"date":"2016-05-01T00:00:00","date_gmt":"2018-12-03T19:34:22","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/beneficial-effect-of-a-polyphenol-rich-diet-on-cardiovascular\/"},"modified":"2018-12-03T20:34:22","modified_gmt":"2018-12-03T19:34:22","slug":"beneficial-effect-of-a-polyphenol-rich-diet-on-cardiovascular","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/beneficial-effect-of-a-polyphenol-rich-diet-on-cardiovascular\/","title":{"rendered":"Beneficial effect of a polyphenol-rich diet on cardiovascular risk: a randomised control trial."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>OBJECTIVES<\/strong><br \/>\nThere is previous epidemiological evidence that intake of polyphenol-rich foods has been associated with reduced cardiovascular disease risk. We aimed to investigate the effect of increasing dietary polyphenol intake on microvascular function in hypertensive participants.<\/p>\n<p style=\"text-align:justify\"><strong>METHODS<\/strong><br \/>\nAll participants completed a 4-week run-in phase, consuming &lt;2 portions of fruit and vegetables (F&amp;V) daily and avoiding berries and dark chocolate. Subjects were then randomised to continue with the low-polyphenol diet for 8\u2005weeks or to consume a high-polyphenol diet of six portions F&amp;V (including one portion of berries\/day and 50\u2005g of dark chocolate). Endothelium-dependent (acetylcholine, ACh) and endothelium-independent (sodium nitroprusside) vasodilator responses were assessed by venous occlusion plethysmography. Compliance with the intervention was measured using food diaries and biochemical markers.<\/p>\n<p style=\"text-align:justify\"><strong>RESULTS<\/strong><br \/>\nFinal analysis of the primary endpoint was conducted on 92 participants. Between-group comparison of change in maximum % response to ACh revealed a significant improvement in the high-polyphenol group (p=0.02). There was a significantly larger increase in vitamin C, carotenoids and epicatechin in the high-polyphenol group (between-group difference p&lt;0.001; p&lt;0.001; p=0.008, respectively).<\/p>\n<p style=\"text-align:justify\"><strong>CONCLUSIONS<\/strong><br \/>\nThis study has shown that increasing the polyphenol content of the diet via consumption of F&amp;V, berries and dark chocolate results in a significant improvement in an established marker of cardiovascular risk in hypertensive participants<strong>.<\/strong><\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-20314","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Centre for Public Health, Queen's University Belfast, Belfast, UK UKCRC Centre of Excellence for Public Health, Queen's University Belfast, Belfast, UK. P.P.McKeown@qub.ac.uk","annee":"2016","mois":"5","numero":":","page":"","auteurs":[{"ID":6702,"post_author":"0","post_date":"2018-12-03 17:40:59","post_date_gmt":"2018-12-03 16:40:59","post_content":"","post_title":"Jayne V Woodside","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jayne-v-woodside","to_ping":"","pinged":"","post_modified":"2018-12-03 17:40:59","post_modified_gmt":"2018-12-03 16:40:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jayne-v-woodside\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6952,"post_author":"0","post_date":"2018-12-03 17:43:44","post_date_gmt":"2018-12-03 16:43:44","post_content":"","post_title":"Ian S Young","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ian-s-young","to_ping":"","pinged":"","post_modified":"2018-12-03 17:43:44","post_modified_gmt":"2018-12-03 16:43:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ian-s-young\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6953,"post_author":"0","post_date":"2018-12-03 17:43:45","post_date_gmt":"2018-12-03 16:43:45","post_content":"","post_title":"Michelle C Mckinley","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"michelle-c-mckinley","to_ping":"","pinged":"","post_modified":"2018-12-03 17:43:45","post_modified_gmt":"2018-12-03 16:43:45","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/michelle-c-mckinley\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9428,"post_author":"0","post_date":"2018-12-03 18:11:02","post_date_gmt":"2018-12-03 17:11:02","post_content":"","post_title":"David R McCance","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"david-r-mccance","to_ping":"","pinged":"","post_modified":"2018-12-03 18:11:02","post_modified_gmt":"2018-12-03 17:11:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/david-r-mccance\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":20310,"post_author":"0","post_date":"2018-12-03 20:34:20","post_date_gmt":"2018-12-03 19:34:20","post_content":"","post_title":"Ciara Rooney","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ciara-rooney","to_ping":"","pinged":"","post_modified":"2018-12-03 20:34:20","post_modified_gmt":"2018-12-03 19:34:20","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ciara-rooney\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":20311,"post_author":"0","post_date":"2018-12-03 20:34:21","post_date_gmt":"2018-12-03 19:34:21","post_content":"","post_title":"Rebecca L Noad","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rebecca-l-noad","to_ping":"","pinged":"","post_modified":"2018-12-03 20:34:21","post_modified_gmt":"2018-12-03 19:34:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/rebecca-l-noad\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9427,"post_author":"0","post_date":"2018-12-03 18:11:02","post_date_gmt":"2018-12-03 17:11:02","post_content":"","post_title":"Damian O McCall","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"damian-o-mccall","to_ping":"","pinged":"","post_modified":"2018-12-03 18:11:02","post_modified_gmt":"2018-12-03 17:11:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/damian-o-mccall\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":20312,"post_author":"0","post_date":"2018-12-03 20:34:21","post_date_gmt":"2018-12-03 19:34:21","post_content":"","post_title":"Pascal P McKeown","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"pascal-p-mckeown","to_ping":"","pinged":"","post_modified":"2018-12-03 20:34:21","post_modified_gmt":"2018-12-03 19:34:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/pascal-p-mckeown\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":20313,"post_author":"0","post_date":"2018-12-03 20:34:22","post_date_gmt":"2018-12-03 19:34:22","post_content":"","post_title":"Heart (British Cardiac Society)","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"heart-british-cardiac-society","to_ping":"","pinged":"","post_modified":"2018-12-03 20:34:22","post_modified_gmt":"2018-12-03 19:34:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/heart-british-cardiac-society\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Beneficial effect of a polyphenol-rich diet on cardiovascular risk: a randomised control trial. - Aprifel<\/title>\n<meta name=\"description\" content=\"Beneficial effect of a polyphenol-rich diet on cardiovascular risk: a randomised control trial. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Beneficial effect of a polyphenol-rich diet on cardiovascular risk: a randomised control trial.\" \/>\n<meta property=\"og:description\" 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