{"id":17719,"date":"2016-08-01T00:00:00","date_gmt":"2018-12-03T18:55:42","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/an-observational-study-to-evaluate-associations-between-low-level\/"},"modified":"2018-12-03T19:55:42","modified_gmt":"2018-12-03T18:55:42","slug":"an-observational-study-to-evaluate-associations-between-low-level","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/an-observational-study-to-evaluate-associations-between-low-level\/","title":{"rendered":"An Observational Study to Evaluate Associations Between Low-Level Gestational Exposure to Organophosphate Pesticides and Cognition During Early Childhood."},"content":{"rendered":"<p style=\"text-align:justify\">Prenatal exposure to organophosphate pesticides, which is ubiquitous, may be detrimental to neurological development. We examined 327 mother\/infant pairs in Cincinnati, Ohio, between 2003 and 2006 to determine associations between prenatal exposure to organophosphate pesticides and neurodevelopment. Twice during pregnancy urinary concentrations of 6 common dialkylphosphates, nonspecific metabolites of organophosphate pesticides, were measured. Aggregate concentrations of diethylphosphates, dimethylphosphates, and total dialkylphosphates were calculated. Bayley Scales of Infant Development, Second Edition-Mental and Psychomotor Developmental indices were administered at ages 1, 2, and 3 years, the Clinical Evaluation of Language Fundamentals-Preschool, Second Edition, at age 4, and the Wechsler Preschool and Primary Scale of Intelligence, Third Edition, at age 5. Mothers with higher urinary total dialkylphosphate concentrations reported higher levels of socioeconomic status and increased fresh fruit and vegetable intake. We found no associations between prenatal exposure to organophosphate pesticides and cognition at 1-5 years of age. In our cohort, exposure to organophosphate pesticides during pregnancy was not associated with cognition during early childhood. It is possible that a higher socioeconomic status and healthier diet may protect the fetus from potential adverse associations with gestational organophosphate pesticide exposure, or that dietary exposure to the metabolites is innocuous and not an ideal measure of exposure to the parent compound.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-17719","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, USA.\r\nstephanie.donauer@cchmc.org","annee":"2016","mois":"8","numero":"184:5","page":"410-8","auteurs":[{"ID":17711,"post_author":"0","post_date":"2018-12-03 19:55:37","post_date_gmt":"2018-12-03 18:55:37","post_content":"","post_title":"Kimberly Yolton","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kimberly-yolton","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:37","post_modified_gmt":"2018-12-03 18:55:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kimberly-yolton\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":17712,"post_author":"0","post_date":"2018-12-03 19:55:38","post_date_gmt":"2018-12-03 18:55:38","post_content":"","post_title":"Yingying Xu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"yingying-xu","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:38","post_modified_gmt":"2018-12-03 18:55:38","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/yingying-xu\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":17713,"post_author":"0","post_date":"2018-12-03 19:55:38","post_date_gmt":"2018-12-03 18:55:38","post_content":"","post_title":"Heidi Sucharew","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"heidi-sucharew","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:38","post_modified_gmt":"2018-12-03 18:55:38","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/heidi-sucharew\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":17714,"post_author":"0","post_date":"2018-12-03 19:55:39","post_date_gmt":"2018-12-03 18:55:39","post_content":"","post_title":"Paul Succop","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"paul-succop","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:39","post_modified_gmt":"2018-12-03 18:55:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/paul-succop\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":17715,"post_author":"0","post_date":"2018-12-03 19:55:40","post_date_gmt":"2018-12-03 18:55:40","post_content":"","post_title":"Mekibib Altaye","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mekibib-altaye","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:40","post_modified_gmt":"2018-12-03 18:55:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mekibib-altaye\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10967,"post_author":"0","post_date":"2018-12-03 18:29:35","post_date_gmt":"2018-12-03 17:29:35","post_content":"","post_title":"Antonia M Calafat","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"antonia-m-calafat","to_ping":"","pinged":"","post_modified":"2018-12-03 18:29:35","post_modified_gmt":"2018-12-03 17:29:35","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/antonia-m-calafat\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":17716,"post_author":"0","post_date":"2018-12-03 19:55:40","post_date_gmt":"2018-12-03 18:55:40","post_content":"","post_title":"Jane C Khoury","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jane-c-khoury","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:40","post_modified_gmt":"2018-12-03 18:55:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jane-c-khoury\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":17717,"post_author":"0","post_date":"2018-12-03 19:55:41","post_date_gmt":"2018-12-03 18:55:41","post_content":"","post_title":"Stephanie Donauer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"stephanie-donauer","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:41","post_modified_gmt":"2018-12-03 18:55:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/stephanie-donauer\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":17718,"post_author":"0","post_date":"2018-12-03 19:55:41","post_date_gmt":"2018-12-03 18:55:41","post_content":"","post_title":"Bruce Lanphear","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bruce-lanphear","to_ping":"","pinged":"","post_modified":"2018-12-03 19:55:41","post_modified_gmt":"2018-12-03 18:55:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bruce-lanphear\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":2252,"post_author":"0","post_date":"2018-12-03 16:53:48","post_date_gmt":"2018-12-03 15:53:48","post_content":"","post_title":"American journal of epidemiology","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"american-journal-of-epidemiology","to_ping":"","pinged":"","post_modified":"2018-12-03 16:53:48","post_modified_gmt":"2018-12-03 15:53:48","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/american-journal-of-epidemiology\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>An Observational Study to Evaluate Associations Between Low-Level Gestational Exposure to Organophosphate Pesticides and Cognition During Early Childhood. - Aprifel<\/title>\n<meta name=\"description\" content=\"An Observational Study to Evaluate Associations Between Low-Level Gestational Exposure to Organophosphate Pesticides and Cognition During Early Childhood. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"An Observational 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