{"id":16550,"date":"2016-10-01T00:00:00","date_gmt":"2018-12-03T18:40:26","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/"},"modified":"2018-12-03T19:40:26","modified_gmt":"2018-12-03T18:40:26","slug":"the-relationship-between-vegetablefruit-consumption-and","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/","title":{"rendered":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan."},"content":{"rendered":"<p style=\"text-align:justify\">Vegetable and fruit consumption may have a protective effect against several types of cancers. However, the effect on biliary cancers is unclear. We investigated the association of vegetable\/fruit consumption with the risks of gallbladder cancer (GBC), intrahepatic bile duct cancer (IHBDC) and extrahepatic bile duct cancer (EHBDC) in a population-based prospective cohort study in Japan. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using the Cox proportional hazard model, and the exposure level was categorized into quartiles, with the lowest group used as the reference. A total of 80,371 people aged 45-74 years were enrolled between 1995 and 1999, and followed up for 1,158,632 person-years until 2012, during which 133 GBC, 99 IHBDC, and 161 EHBDC cases were identified. Increased consumption of total vegetable and fruit was significantly associated with a decreased risk of EHBDC (HR = 0.49; 95% CI: 0.29-0.81 for the highest group; P-trend = 0.005). From the analysis of relevant nutrients, significantly decreased risk of EHBDC was associated with folate and insoluble fiber (HR = 0.48, 0.53; 95% CI: 0.28-0.85, 0.31-0.88 for the highest group; P-trend = 0.010, 0.023; respectively), and a significant trend of decreased EHBDC risk associated with vitamin C was observed (P-trend = 0.029). No decreased risk of GBC and IHBDC was found. Our findings suggest that increased vegetable\/fruit consumption may decrease a risk of EHBDC, and folate, vitamin C, and insoluble fiber might be key contributors to the observed protective effect.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-16550","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Environmental Medicine and Population Sciences, Graduate School of Medicine, Osaka University, Suita Osaka, 565-0871, Japan.","annee":"2016","mois":"10","numero":":","page":"","auteurs":[{"ID":6679,"post_author":"0","post_date":"2018-12-03 17:40:44","post_date_gmt":"2018-12-03 16:40:44","post_content":"","post_title":"Shoichiro Tsugane","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"shoichiro-tsugane","to_ping":"","pinged":"","post_modified":"2018-12-03 17:40:44","post_modified_gmt":"2018-12-03 16:40:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/shoichiro-tsugane\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6680,"post_author":"0","post_date":"2018-12-03 17:40:44","post_date_gmt":"2018-12-03 16:40:44","post_content":"","post_title":"Motoki Iwasaki","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"motoki-iwasaki","to_ping":"","pinged":"","post_modified":"2018-12-03 17:40:44","post_modified_gmt":"2018-12-03 16:40:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/motoki-iwasaki\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":13532,"post_author":"0","post_date":"2018-12-03 18:59:17","post_date_gmt":"2018-12-03 17:59:17","post_content":"","post_title":"Shizuka Sasazuki","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"shizuka-sasazuki","to_ping":"","pinged":"","post_modified":"2018-12-03 18:59:17","post_modified_gmt":"2018-12-03 17:59:17","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/shizuka-sasazuki\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6681,"post_author":"0","post_date":"2018-12-03 17:40:45","post_date_gmt":"2018-12-03 16:40:45","post_content":"","post_title":"Norie Sawada","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"norie-sawada","to_ping":"","pinged":"","post_modified":"2018-12-03 17:40:45","post_modified_gmt":"2018-12-03 16:40:45","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/norie-sawada\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6682,"post_author":"0","post_date":"2018-12-03 17:40:45","post_date_gmt":"2018-12-03 16:40:45","post_content":"","post_title":"Taiki Yamaji","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"taiki-yamaji","to_ping":"","pinged":"","post_modified":"2018-12-03 17:40:45","post_modified_gmt":"2018-12-03 16:40:45","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/taiki-yamaji\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6683,"post_author":"0","post_date":"2018-12-03 17:40:46","post_date_gmt":"2018-12-03 16:40:46","post_content":"","post_title":"Taichi Shimazu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"taichi-shimazu","to_ping":"","pinged":"","post_modified":"2018-12-03 17:40:46","post_modified_gmt":"2018-12-03 16:40:46","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/taichi-shimazu\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":6684,"post_author":"0","post_date":"2018-12-03 17:40:46","post_date_gmt":"2018-12-03 16:40:46","post_content":"","post_title":"Junko Ishihara","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"junko-ishihara","to_ping":"","pinged":"","post_modified":"2018-12-03 17:40:46","post_modified_gmt":"2018-12-03 16:40:46","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/junko-ishihara\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":16548,"post_author":"0","post_date":"2018-12-03 19:40:25","post_date_gmt":"2018-12-03 18:40:25","post_content":"","post_title":"Takeshi Makiuchi","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"takeshi-makiuchi","to_ping":"","pinged":"","post_modified":"2018-12-03 19:40:25","post_modified_gmt":"2018-12-03 18:40:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/takeshi-makiuchi\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":13534,"post_author":"0","post_date":"2018-12-03 18:59:19","post_date_gmt":"2018-12-03 17:59:19","post_content":"","post_title":"Tomotaka Sobue","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"tomotaka-sobue","to_ping":"","pinged":"","post_modified":"2018-12-03 18:59:19","post_modified_gmt":"2018-12-03 17:59:19","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/tomotaka-sobue\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":16549,"post_author":"0","post_date":"2018-12-03 19:40:26","post_date_gmt":"2018-12-03 18:40:26","post_content":"","post_title":"Tetsuhisa Kitamura","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"tetsuhisa-kitamura","to_ping":"","pinged":"","post_modified":"2018-12-03 19:40:26","post_modified_gmt":"2018-12-03 18:40:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/tetsuhisa-kitamura\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":4186,"post_author":"0","post_date":"2018-12-03 17:13:15","post_date_gmt":"2018-12-03 16:13:15","post_content":"","post_title":"INTERNATIONAL JOURNAL OF CANCER","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"international-journal-of-cancer","to_ping":"","pinged":"","post_modified":"2018-12-03 17:13:15","post_modified_gmt":"2018-12-03 16:13:15","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/international-journal-of-cancer\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel<\/title>\n<meta name=\"description\" content=\"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan.\" \/>\n<meta property=\"og:description\" content=\"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/\",\"name\":\"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-03T18:40:26+00:00\",\"dateModified\":\"2018-12-03T18:40:26+00:00\",\"description\":\"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel","description":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan.","og_description":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan.","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/","name":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-03T18:40:26+00:00","dateModified":"2018-12-03T18:40:26+00:00","description":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan. - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-relationship-between-vegetablefruit-consumption-and\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"The relationship between vegetable\/fruit consumption and gallbladder\/bile duct cancer: A population-based cohort study in Japan."}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/16550"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=16550"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=16550"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}