{"id":13856,"date":"2017-04-01T00:00:00","date_gmt":"2018-12-03T18:03:03","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/foods-and-beverages-and-colorectal-cancer-risk-a-systematic-2\/"},"modified":"2018-12-03T19:03:03","modified_gmt":"2018-12-03T18:03:03","slug":"foods-and-beverages-and-colorectal-cancer-risk-a-systematic-2","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/foods-and-beverages-and-colorectal-cancer-risk-a-systematic-2\/","title":{"rendered":"Foods and beverages and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, an update of the evidence of the WCRF-AICR Continuous Update Project."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>Objective<\/strong><br \/>\nAs part of the World Cancer Research Fund International Continuous Update Project, we updated the systematic review and meta-analysis of prospective studies to quantify the dose-response between foods and beverages intake and colorectal cancer risk.<\/p>\n<p style=\"text-align:justify\"><strong>Data Sources<\/strong><br \/>\nPubMed and several databases up to May 31 st 2015.<\/p>\n<p style=\"text-align:justify\"><strong>Study selection<\/strong><br \/>\nProspective studies reporting adjusted relative risk estimates for the association of specific food groups and beverages and risk of colorectal, colon and rectal cancer.<\/p>\n<p style=\"text-align:justify\"><strong>Data synthesis<\/strong><br \/>\nDose-response meta-analyses using random effect models to estimate summary relative risks (RRs).<\/p>\n<p style=\"text-align:justify\"><strong>Results<\/strong><br \/>\nResults: 400 individual study estimates from 111 unique cohort studies were included. Overall, the risk increase of colorectal cancer is 12% for each 100g\/day increase of red and processed meat intake (95%CI=4-21%, I2 =70%, pheterogeneity (ph)&lt;0.01) and 7% for 10&thinsp;g\/day increase of ethanol intake in alcoholic drinks (95%CI=5-9%, I2 =25%, ph&thinsp;=&thinsp; 0.21). Colorectal cancer risk decrease in 17% for each 90g\/day increase of whole grains (95%CI=11-21%, I2 =0%, ph&thinsp;=&thinsp; 0.30, 6 studies). For each 400&thinsp;g\/day increase of dairy products intake (95%CI=10-17%, I2 =18%, ph&thinsp;=&thinsp; 0.27, 10 studies). Inverse associations were also observed for vegetables intake (RR per 100&thinsp;g\/day =0.98 (95%CI=0.96-0.99, I2 =0%, ph&thinsp;=&thinsp; 0.48, 11 studies) and for fish intake (RR for 100g\/day=0.89(95%CI=0.80-0.99, I2 =0%, ph&thinsp;=&thinsp; 0.52, 11 studies), that were weak for vegetables and driven by one study for fish. Intakes of fruits, coffee, tea, cheese, poultry and legumes were not associated with colorectal cancer risk.<\/p>\n<p style=\"text-align:justify\"><strong>Conclusions<\/strong><br \/>\nOur results reinforce the evidence that high intake of red and processed meat and alcohol increase the risk of colorectal cancer. Milk and whole grains may have a protective role against colorectal cancer. The evidence for vegetables and fish was less convincing.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-13856","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.","annee":"2017","mois":"4","numero":"","page":"","auteurs":[{"ID":9017,"post_author":"0","post_date":"2018-12-03 18:06:26","post_date_gmt":"2018-12-03 17:06:26","post_content":"","post_title":"Teresa Norat","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"teresa-norat","to_ping":"","pinged":"","post_modified":"2018-12-03 18:06:26","post_modified_gmt":"2018-12-03 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Vingeliene","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"s-vingeliene","to_ping":"","pinged":"","post_modified":"2018-12-03 18:42:26","post_modified_gmt":"2018-12-03 17:42:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/s-vingeliene\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":12076,"post_author":"0","post_date":"2018-12-03 18:42:27","post_date_gmt":"2018-12-03 17:42:27","post_content":"","post_title":"L Abar","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"l-abar","to_ping":"","pinged":"","post_modified":"2018-12-03 18:42:27","post_modified_gmt":"2018-12-03 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Polemiti","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"e-polemiti","to_ping":"","pinged":"","post_modified":"2018-12-03 18:42:28","post_modified_gmt":"2018-12-03 17:42:28","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/e-polemiti\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7925,"post_author":"0","post_date":"2018-12-03 17:54:23","post_date_gmt":"2018-12-03 16:54:23","post_content":"","post_title":"Carl Stevenson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"carl-stevenson","to_ping":"","pinged":"","post_modified":"2018-12-03 17:54:23","post_modified_gmt":"2018-12-03 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