{"id":12650,"date":"2017-02-01T00:00:00","date_gmt":"2018-12-03T17:48:56","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/mediterranean-dietary-pattern-and-vegf-405-gc-gene-polymorphisms\/"},"modified":"2018-12-03T18:48:56","modified_gmt":"2018-12-03T17:48:56","slug":"mediterranean-dietary-pattern-and-vegf-405-gc-gene-polymorphisms","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/mediterranean-dietary-pattern-and-vegf-405-gc-gene-polymorphisms\/","title":{"rendered":"Mediterranean dietary pattern and VEGF +405 G\/C gene polymorphisms in patients with metabolic syndrome: An aspect of gene-nutrient interaction."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>AIMS<\/strong><br \/>\nTo evaluate the relationship between Mediterranean dietary pattern, anthropometric and metabolic biomarkers and vascular endothelial growth factor (VEGF) +405 G\/C gene polymorphism in patient with metabolic syndrome (Mets).<\/p>\n<p style=\"text-align:justify\"><strong>MATERIALS AND METHODS<\/strong><br \/>\nIn this study 150 patients with Mets and 50 healthy subjects were enrolled. Dietary intakes were evaluated with a semi-quantitative food-frequency questionnaire (FFQ) and Mediterranean dietary quality index (Med-DQI) was assessed. Anthropometric assessments and blood pressure measurement were performed. Biochemical assays including fasting serum glucose (FSG), matrix metalloproteinase-3 (MMP-3), liver enzymes and lipid profiles were also assessed. Polymorphism of +405 G\/C VEGF gene was determined utilizing polymerase chain reaction-restriction fragments length polymorphism (PCR-RFLP) method.<\/p>\n<p style=\"text-align:justify\"><strong>RESULTS<\/strong><br \/>\nSerum high density lipoprotein-cholesterol (HDL-C) was significantly lower and low density lipoprotein cholesterol (LDL-C), triglyceride (TG), total cholesterol (TC) concentrations and FSG were significantly higher in metabolic syndrome patients compared with control group (P &lt; 0.05). Metabolic syndrome group with high consumption of &quot;cholesterol&quot; had significantly upper serum TG; also high consumption of &quot;fish&quot; and &quot;vegetables-fruits&quot; was associated with a significantly lower serum LDL concentrations. In metabolic syndrome patients with CC genotype, mean score of &quot;saturated fatty acid&quot; subgroup was significantly higher compared with other genotypes; whereas, in healthy individuals, mean score of &quot;fruit-vegetable&quot; subgroup in individuals of CC and GG genotype was significantly higher (P&lt;0.05).<\/p>\n<p style=\"text-align:justify\"><strong>CONCLUSION<\/strong><br \/>\nOur findings indicated a significant relationship between Mediterranean dietary quality index and both anthropometric and metabolic risk factors. We also indicated a higher &quot;saturated fatty acid&quot; intake in CC genotype among metabolic syndrome patients.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-12650","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Student Research Committee, Nutrition Research Center, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.","annee":"2017","mois":"2","numero":"12:2","page":"","auteurs":[{"ID":12647,"post_author":"0","post_date":"2018-12-03 18:48:55","post_date_gmt":"2018-12-03 17:48:55","post_content":"","post_title":"Ghazaleh Hajiluian","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ghazaleh-hajiluian","to_ping":"","pinged":"","post_modified":"2018-12-03 18:48:55","post_modified_gmt":"2018-12-03 17:48:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ghazaleh-hajiluian\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":12648,"post_author":"0","post_date":"2018-12-03 18:48:55","post_date_gmt":"2018-12-03 17:48:55","post_content":"","post_title":"Mahdieh Abbasalizad Farhangi","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mahdieh-abbasalizad-farhangi","to_ping":"","pinged":"","post_modified":"2018-12-03 18:48:55","post_modified_gmt":"2018-12-03 17:48:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mahdieh-abbasalizad-farhangi\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":12649,"post_author":"0","post_date":"2018-12-03 18:48:56","post_date_gmt":"2018-12-03 17:48:56","post_content":"","post_title":"Leila Jahangiry","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"leila-jahangiry","to_ping":"","pinged":"","post_modified":"2018-12-03 18:48:56","post_modified_gmt":"2018-12-03 17:48:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/leila-jahangiry\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1142,"post_author":"0","post_date":"2018-12-03 15:56:43","post_date_gmt":"2018-12-03 14:56:43","post_content":"","post_title":"PloS one","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"plos-one","to_ping":"","pinged":"","post_modified":"2018-12-03 15:56:43","post_modified_gmt":"2018-12-03 14:56:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/plos-one\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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