{"id":10593,"date":"2017-09-01T00:00:00","date_gmt":"2018-12-03T17:25:27","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/adherence-to-the-western-prudent-and-mediterranean-dietary-2\/"},"modified":"2018-12-03T18:25:27","modified_gmt":"2018-12-03T17:25:27","slug":"adherence-to-the-western-prudent-and-mediterranean-dietary-2","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/adherence-to-the-western-prudent-and-mediterranean-dietary-2\/","title":{"rendered":"Adherence to the Western, Prudent and Mediterranean dietary patterns and breast cancer risk: MCC-Spain study."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>OBJECTIVE<\/strong><br \/>\nTo externally validate the previously identified effect on breast cancer risk of the Western, Prudent and Mediterranean dietary patterns.<\/p>\n<p style=\"text-align:justify\"><strong>STUDY DESIGN<\/strong><br \/>\nMCC-Spain is a multicase-control study that collected epidemiological information on 1181 incident cases of female breast cancer and 1682 healthy controls from 10 Spanish provinces. Three dietary patterns derived in another Spanish case-control study were analysed in the MCC-Spain study. These patterns were termed Western (high intakes of fatty and sugary products and red and processed meat), Prudent (high intakes of low-fat dairy products, vegetables, fruits, whole grains and juices) and Mediterranean (high intake of fish, vegetables, legumes, boiled potatoes, fruits, olives, and vegetable oil, and a low intake of juices). Their association with breast cancer was assessed using logistic regression models with random province-specific intercepts considering an interaction with menopausal status. Risk according to tumour subtypes &#8211; based on oestrogen (ER), progesterone (PR) and human epidermal growth factor 2 (HER2) receptors (ER+\/PR+ &amp; HER2-; HER2+; ER-\/PR- &amp; HER2-) &#8211; was evaluated with multinomial regression models.<\/p>\n<p style=\"text-align:justify\"><strong>MAIN OUTCOME MEASURES<\/strong><br \/>\nBreast cancer and histological subtype.<\/p>\n<p style=\"text-align:justify\"><strong>RESULTS<\/strong><br \/>\nOur results confirm most of the associations found in the previous case-control study. A high adherence to the Western dietary pattern seems to increase breast cancer risk in both premenopausal women (OR4(th)vs.1(st)quartile (95% CI):1.68 (1.02;2.79); OR1SD-increase (95% CI):1.19 (1.02;1.40)) and postmenopausal women (OR4(th)vs.1(st)quartile(95% CI):1.48(1.07;2.05); OR1SD-increase(95% CI): 1.14 (1.01;1.29)). While high adherence to the Prudent pattern did not show any effect on breast cancer, the Mediterranean dietary pattern seemed to be protective, but only among postmenopausal women (OR4(th)vs.1(st)quartile (95% CI): 0.72 (95% CI 0.53;0.98); p-int=0.075). There were no significant differences by tumour subtype.<\/p>\n<p style=\"text-align:justify\"><strong>CONCLUSION<\/strong><br \/>\nDietary recommendations based on a departure from the Western dietary pattern in favour of the Mediterranean diet could reduce breast cancer risk in the general population.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-10593","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Cancer Epidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain; Cancer Epidemiology Research Group, Oncology and Hematology Area, IIS Puerta de Hierro (IDIPHIM), Manuel de Falla 1, 28222, Madrid, Spain. Electronic address: acastello@isciii.es.","annee":"2017","mois":"9","numero":"103:","page":"8-15","auteurs":[{"ID":3371,"post_author":"0","post_date":"2018-12-03 17:04:56","post_date_gmt":"2018-12-03 16:04:56","post_content":"","post_title":"Pilar Amiano","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"pilar-amiano","to_ping":"","pinged":"","post_modified":"2018-12-03 17:04:56","post_modified_gmt":"2018-12-03 16:04:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/pilar-amiano\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":10586,"post_author":"0","post_date":"2018-12-03 18:25:23","post_date_gmt":"2018-12-03 17:25:23","post_content":"","post_title":"Adonina 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