Differences in Response to a Dietary Intervention Between the General Population and First-Degree Relatives of Colorectal Cancer Patients.

Auteur(s) :
McClish D., Carcaise-Edinboro P., Esinhart H., Wilson DB., Bean MK.
Date :
Avr, 2014
Source(s) :
Journal of nutrition education and behavior. #: p
Adresse :
Department of Biostatistics and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA. Electronic address: [email protected]

Sommaire de l'article
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OBJECTIVE
To determine whether response to a dietary intervention is greater among people with family history of colorectal cancer (CRC) compared with a general population.

DESIGN
Cohort study examining participants from 2 related studies.

SETTING
Rural Virginia.

PARTICIPANTS
Seventy people with first-degree relatives with CRC and 113 participants from the intervention arm of a trial in the general population.

INTERVENTION
Both studies implemented a low-intensity intervention delivered via telephone and mail, including low-literacy self-help booklets and personalized dietary feedback.

MAIN OUTCOME MEASURES
Fat, fiber, and fruit and vegetable behavior.

ANALYSIS
Propensity score matching controlled for confounders. Mixed-model ANOVAs compared samples; mediation by perceived cancer risk was assessed.

RESULTS
Participants in both groups significantly improved fat, fiber, and fruit and vegetable behavior at 1-month follow-up; there was significantly greater improvement in the general population sample. Cancer risk perception did not mediate the relationship between study sample and dietary change.

CONCLUSIONS AND IMPLICATIONS
Contrary to expectations, first-degree relatives of CRC patients did not respond better to a dietary intervention than the general population, nor was risk perception related to dietary change. Given the role of diet in CRC risk, additional research should investigate targeted strategies to improve dietary intakes of people at higher cancer risk.

Source : Pubmed
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