{"id":71070,"date":"2020-05-13T17:41:09","date_gmt":"2020-05-13T15:41:09","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/?post_type=article_revue&p=71070"},"modified":"2020-05-13T17:41:09","modified_gmt":"2020-05-13T15:41:09","slug":"fruits-and-vegetables-and-the-risk-of-type-2-diabetes-is-there-an-association","status":"publish","type":"article_revue","link":"https:\/\/aprifel-pp.mentalworks.biz\/en\/global-fv-newsletter-article\/fruits-and-vegetables-and-the-risk-of-type-2-diabetes-is-there-an-association\/","title":{"rendered":"Fruits and vegetables and the risk of type 2 diabetes is there an association?"},"content":{"rendered":"

The global burden of diabetes is increasing, with the latest data from the International Diabetes Federation estimating a prevalence of 285 million in 2010, increasing to a staggering 439 million by 20301<\/sup>. The increased premature ill health, reduced life expectancy, and increased death rate related to the presence of diabetes, provide reason for concern, and make its prevention a major public health priority. That the primary prevention of diabetes is possible through lifestyle behaviours, including a healthy diet, has now been well established by intervention trials among people at high risk of diabetes2<\/sup>. However, what the specific contribution might be of the intake of fruits and vegetables to diabetes prevention, is unresolved.<\/p>\n

We hypothesised that the inconsistent findings3-5<\/sup> for an association between intake of fruit\/vegetables and the risk of type 2 diabetes might be explained by the known imprecision and measurement error in assessing fruit\/vegetable intake from selfreport methods such as the food frequency questionnaire. We thus aimed to examine the association of plasma vitamin C, an objective biomarker of fruit\/vegetable intake, and the risk of future diabetes. We also examined the association of diab\u00e8tes with self-reported fruit and vegetable intake.<\/span><\/p>\n

The EPIC<\/span>-Norfolk Study<\/span><\/h1>\n

The European Prospective Investigation of Cancer-Norfolk (EPICNorfolk) study is a population-based cohort study. Men and women aged 40-75 years, resident in Norfolk, U.K. were identified from family-doctor age-sex registers, and of 77,754 invited, 25,639 attended for a health check visit in 1993-97. Dietary intake was assessed by a semi-quantitative food frequency questionnaire and vitamin C was measured in blood (plasma) samples. After exclusions, 21,831 individuals (9,815 men; 12,016 women) were eligible for analysis. Participants were without known diabetes at baseline, and we ascertained new-onset diabetes (n=735) over 12 years of follow up6<\/sup>.<\/span><\/p>\n

An association might be obscured by measurement error<\/span><\/h1>\n

There was a striking inverse association between plasma vitamin C concentration and the risk of new-onset diabetes, while the association with total fruit\/vegetable intake was modest, and lacked the \u2018dose-response\u2019 effect seen with plasma vitamin C (Figure)6. The risk of diabetes in the top fifth (compared to bottom fifth) of the plasma vitamin C distribution was 62% lower (95% confidence limits 48% to 72% lower), while for a similar comparison for fruit\/vegetable intake there was a modest 22% reduction in risk of diabetes (95% confidence limits 0% to 40% lower risk). These analyses accounted for other factors, such as potential healthier lifestyles among those who eat greater quantities of fruit\/vegetable or have higher vitamin C levels [adjusting for age, sex, family history of diabetes, lifestyle factors (alcohol intake, smoking, physical activity), socio-economic status (education, social class), obesity (body mass index and waist circumference), and intake of vitamin supplements].<\/span><\/p>\n

Conclusions<\/span><\/h1>\n

Evidence for the benefits of greater intake of fruits\/vegetables for diabetes prevention is elicited strongly and convincingly when plasma vitamin C (a valid biomarker) is used as a proxy for fruit and vegetable intake. In contrast, the same association is attenuated and more modest when self-reported fruit\/vegetable intake is used. Because fruit and vegetables are the main source of vitamin C, these findings suggest that eating even a small quantity of fruit\/vegetables may be beneficial and that the protection against diabetes increases progressively with the quantity of fruit and vegetables consumed.<\/span><\/p>\n

\"\"<\/p>\n","protected":false},"template":"","class_list":["post-71070","article_revue","type-article_revue","status-publish","hentry"],"acf":{"auteur":"","source":"","revue":[{"ID":70487,"post_author":"22","post_date":"2020-04-21 09:05:13","post_date_gmt":"2020-04-21 07:05:13","post_content":"","post_title":"56 - May 2011","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"56-may-2011","to_ping":"","pinged":"","post_modified":"2020-04-21 09:05:13","post_modified_gmt":"2020-04-21 07:05:13","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/?post_type=revue&p=70487","menu_order":266,"post_type":"revue","post_mime_type":"","comment_count":"0","filter":"raw"}],"position":"2","references":"

    \n
  1. Shaw JE et al. [2010] Diabetes Res Clin Pract 87, 4-14.
    \n<\/span><\/li>\n
  2. Gillies CL et al. [2007] Br Med 334, 299-307.
    \n<\/span><\/li>\n
  3. Hamer M et al. [2007] J Hypertens 25, 2361-2369.
    \n<\/span><\/li>\n
  4. Liu S et al. [2004] Diabetes Care 27, 2993-2996
    \n<\/span><\/li>\n
  5. Bazzano LA et al. [2008] Diabetes Care 31, 1311-1317.
    \n<\/span><\/li>\n
  6. Harding AH et al. [2008] Arch Intern Med 168,1493-1499.<\/span><\/li>\n<\/ol>\n"},"yoast_head":"\nFruits and vegetables and the risk of type 2 diabetes is there an association? \u00c9quation Nutrition - Aprifel<\/title>\n<meta name=\"description\" content=\"Fruits and vegetables and the risk of type 2 diabetes is there an association? \u00c9quation Nutrition - Aprifel\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/aprifel-pp.mentalworks.biz\/en\/global-fv-newsletter-article\/fruits-and-vegetables-and-the-risk-of-type-2-diabetes-is-there-an-association\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fruits and vegetables and the risk of type 2 diabetes is there an association? \u00c9quation Nutrition\" \/>\n<meta property=\"og:description\" content=\"Fruits and vegetables and the risk of type 2 diabetes is there an association? 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